CD8+ T cell immunity enhances tumor cell susceptibility to cuproptosis, improving the effectiveness of inducers in overcoming immunotherapy resistance in preclinical models.
- Open access
- 11 cites
Ferroptosis and cancer prognosis
Moving in Cell.
- Moved this week
- 1
Rebuilt
Moved this week
Latest in Ferroptosis and cancer prognosis
Newest first · last 60 days
Dietary unsaturated fatty acids differentially influence pancreatic cancer progression by modulating ferroptosis sensitivity, with MUFAs promoting and PUFAs inhibiting tumor development.
- Open access
- 1 cites
Loss of KDM6A enhances oxidative phosphorylation across multiple tissues, revealing a conserved mechanism of tissue-level convergent evolution in cancer and development.
- Open access
ArchMap enables accessible, no-code reference-based analysis of single-cell datasets, democratizing the use of comprehensive atlases for researchers worldwide.
- Open access
SpaCEy, an explainable graph neural network, predicts clinical outcomes from spatial proteomics data with 100% accuracy in identifying key tissue patterns.
- Open access
S1PR1, CA2, and ABCG2 are identified as key ion homeostasis-related genes with strong diagnostic potential for pulmonary arterial hypertension, with S1PR1 showing protective effects.
- Open access
Personalized single-cell transcriptomics uncovers molecular diversity in over 1900 brains with Alzheimer's disease, revealing distinct subpopulations and disease trajectories.
- Open access
- 1 cites
An iron-dependent methionine redox pathway controls adipose browning and cachexia, with MsrA deletion reducing cachexia and extending survival in mouse models.
- Open access
- 1 cites
Lactobacillus plantarum and its metabolite indole-3-lactic acid restore skin barrier function by modulating the clock-ferroptosis axis in psoriasis.
- Open access
Metastasis-to-metastasis seeding dominates bladder cancer spread, with heterogeneity and early driver alterations linked to poor prognosis in specific subtypes.
- Open access
Mitochondrial fission factor phosphorylation at Ser155 drives ferroptosis by promoting organelle fragmentation and oxidative stress in cells.
Multi-omics and AI integration reveal complex cancer microbiome patterns, advancing understanding and potential clinical applications.
- 1 opens in JClub
- Open access
Virtual tumor models accurately predict personalized therapeutic combinations for NSCLC, identifying 53BP1 as a promising target and stratifying patients for radiotherapy.
Inhibiting PPM1D disrupts mitochondrial integrity, activates cGAS-STING signaling, and enhances antitumor immunity in hepatocellular carcinoma models.
A nomogram combining tumor-immune and nutritional biomarkers predicts 3-year recurrence with 84.1% accuracy after total colectomy for advanced colon cancer.
- Open access
Copper ion-induced MYH9 polymerization triggers cuproptosis, with 50% of drug-resistant tumor cells showing elevated copper levels facilitating this process.
- Open access
NINJ2 maintains lysosomal membrane integrity to prevent ferroptosis, with loss increasing susceptibility by 2.5-fold in cell models.
- Open access
A 9-gene signature predicts radiotherapy outcomes in hypopharyngeal squamous cell carcinoma with over 82% accuracy at 1 year.
- Open access
Follow this area in the app
Browse JClub
Journals this month
- bioRxiv5569
- medRxiv1746
- Environ Res483
- PNAS463
- Sci Adv439
- JAMA255
- Cell Rep210
- BMJ199
- Nat Commun177
- Environ Pollution170
- Lancet149
- Science138
- NEJM119
- Applied & Environ Microbio116
- J Exp Bot115
- Curr Biol112
- mBio109
- Nature104
Moving areas, week to 3 Oct 2026
- Single-cell and spatial transcriptomics10
- Artificial Intelligence in Healthcare and Education8
- CAR-T cell therapy research7
- Neuroinflammation and Neurodegeneration Mechanisms6
- Lung Cancer Treatments and Mutations5
- Diabetes Treatment and Management4
- Pancreatic and Hepatic Oncology Research4
- Photosynthetic Processes and Mechanisms4
- Genomics and Chromatin Dynamics4
- Gut microbiota and health4