European Heart Journal

AI summary · may contain errors

Higher white blood cell count is strongly associated with greater 6-year subclinical atherosclerosis plaque burden in 3,471 middle-aged asymptomatic participants, increasing global plaque volume by 32.6% per 1 SD.

AI summary · may contain errors

A 48 g/day increment in whole-grain intake in randomized trials is linked to lower body weight by a mean difference of -0.20 kg (95% CI -0.31 to -0.09; n=41).

AI summary · may contain errors

A structured collaboration framework for academia–medical industry partnerships defines six integrity principles—transparency, independence, accountability, equity, sustainability, and patient-centred benefit—to strengthen governance.

AI summary · may contain errors

In 508 hypertrophic cardiomyopathy patients with prior negative NGS testing, retesting with an updated panel found HCM-related variants in 9% (46/508), including new and reclassified findings.

AI summary · may contain errors

Sacubitril/valsartan prophylaxis is linked to improved left ventricular global longitudinal strain and aortic compliance in paediatric post-radiotherapy patients, with a favourable safety profile.

AI summary · may contain errors

In the FINE-HEART pooled analysis of 18 991 advanced cardiovascular-kidney-metabolic participants, women had higher multimorbidity and lower all-cause mortality risk (adjusted HR 0.83).

AI summary · may contain errors

The Acute Aortic Syndrome Rule-Out Criteria (ARC) identifies low-risk suspected acute aortic syndrome patients with 100% sensitivity in external cohorts, enabling safe rule-out without missing cases.

AI summary · may contain errors

Prophylactic SynFlow 3.0 micro-axial flow pump during non-emergent high-risk PCI in patients with LVEF ≤35% is non-inferior to VA-ECMO for 30-day major adverse events (7.34% vs 11.5%).

AI summary · may contain errors

Beta-blocker trial participants in BETAMI-DANBLOCK had lower 3-year absolute risk of all-cause mortality or MI (7.7%–7.8%) than Norway’s NORMI revascularized MI cohort (12.0%).

AI summary · may contain errors

In CRT candidates with typical left bundle branch block, left-bundle branch area pacing did not meet non-inferiority versus biventricular pacing for 6-month positive response (89.7% vs 94.6%).

AI summary · may contain errors

In 2057 post-hospitalization acute coronary syndrome patients, a nurse-coordinated prevention program reduced long-term MACE versus standard care (16.2% vs 22.6%; HR 0.70).