NCFlow enables the placement of any non-canonical amino acid into proteins, outperforming existing methods in structure prediction for unseen ncAAs.
- 7 cites
RNA and protein synthesis mechanisms
Moving in Bioinformatics, EMBO Journal.
- Moved this week
- 2
Rebuilt
Moved this week
AHA, a conserved archaeal ribosome-associated protein, links bacterial hibernation factors and eukaryotic energy sensors, revealing an evolutionary connection across domains.
- Open access
Latest in RNA and protein synthesis mechanisms
Newest first · last 60 days
AHA, a conserved archaeal ribosome-associated protein, links bacterial hibernation factors and eukaryotic energy sensors, revealing an evolutionary connection across domains.
- Open access
De novo RNA-guided transposition systems using TnpB-family proteins achieve high-efficiency DNA insertion with precise control in bacteria.
- Open access
Genetic code expansion enables multiplex noncanonical amino acid incorporation through codon compression and novel codon creation, expanding protein engineering capabilities.
Nuclear stress-induced modification of NCBP1 at cysteine 436 causes alternative splicing of over 250 genes, including S6 kinase, leading to translation inhibition.
- Open access
- 1 cites
Cell surface RNA-binding proteins are emerging as potential biomarkers and immunotherapy targets, with specificities linked to cell type and disease, including cancer.
A human cell-free translation screen identified NT-2 as a novel ribosomal inhibitor binding the peptidyl transferase center, disrupting mammalian protein synthesis.
- Open access
FoldaVirus predicts complete icosahedral viral capsids up to T=9 symmetry by integrating AlphaFold structures with known viral architectures.
- Open access
iModulon framework reveals a conserved "regulatory toolkit" of 13 modules across 53 bacterial species from over 33,000 RNA-seq samples.
- Open access
Generative AI-designed thiolation domains enable up to threefold increased yields in reprogrammed non-ribosomal peptide synthetases.
- Open access
Deletion of mraW reduces translation efficiency by approximately twofold in Bacillus subtilis ribosomes, correcting a sporulation defect and bypassing a checkpoint.
- Open access
- 1 cites
Dormant bacteria gradually eliminate RNA phages over days through ROS-mediated RNA damage, explaining their scarcity in natural environments.
- Open access
Integration of full-length mRNA sequencing and proteomics reveals approximately 14,000 protein isoforms in human cells, highlighting extensive proteome diversity.
- Open access
- 2 cites
Follow this area in the app
Browse JClub
Journals this month
- bioRxiv5569
- medRxiv1746
- Environ Res483
- PNAS463
- Sci Adv439
- JAMA255
- Cell Rep210
- BMJ199
- Nat Commun177
- Environ Pollution170
- Lancet149
- Science138
- NEJM119
- Applied & Environ Microbio116
- J Exp Bot115
- Curr Biol112
- mBio109
- Nature104
Moving areas, week to 3 Oct 2026
- Single-cell and spatial transcriptomics10
- Artificial Intelligence in Healthcare and Education8
- CAR-T cell therapy research7
- Neuroinflammation and Neurodegeneration Mechanisms6
- Lung Cancer Treatments and Mutations5
- Diabetes Treatment and Management4
- Pancreatic and Hepatic Oncology Research4
- Photosynthetic Processes and Mechanisms4
- Genomics and Chromatin Dynamics4
- Gut microbiota and health4