Nature Cell Biology
Nature Portfolio · Cell & Molecular Biology · ISSN 1465-7392, 1476-4679
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Latest in Nat Cell Biol
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Clathrin-mediated endocytosis shows only minor selectivity for cytoplasmic leaflet lipids, with lipid partitioning differences ranging from slight enrichment to moderate exclusion.
Multiomic analysis of human meningeal development from 6 to 21 weeks reveals key cellular and regulatory programs, including lineage origins and immune dynamics.
Meningiomas originate from dura-lineage cells, as shown by their transcriptional similarity to fetal dura tissue, highlighting a dura-like nature of these tumors.
DePass achieves superior multi-omics data integration across six modalities and 13 platforms, revealing detailed tissue heterogeneity at near single-cell resolution.
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Taxanes activate RhoA signalling by inducing conformational changes in microtubule lattice that release GEF-H1, with rapid effects observed in interphase cells.
CLN8 is a stereospecific acyltransferase essential for BMP biosynthesis, with mutations impairing its activity linked to Batten disease in mice and zebrafish.
DFCP1 mediates lysosomal membrane repair by concentrating ER-associated lipid transport machinery at damaged lysosomes, crucial for cellular resistance to vacuolar damage.
CLN8 enables a non-canonical phospholipid synthesis pathway crucial for lysosomal lipid homeostasis, with deficiency causing lipid accumulation in Batten disease models.
Intergenic suppressors in tubulin genes restore microtubule dynamics and rescue dominant-negative tubulinopathies, with over 70% outperforming wild-type tubulin in human cells.
Bipartite active X chromosome structure dissolves in liver cancer, with significant implications for tumor development.
Tissue flows guide immune cell polarization and migration, with local ectodermal flows directing embryonic myeloid cell dispersion in Xenopus embryos.
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Distinct epithelial and fibroblast features in pancreatitis and PDAC are revealed through multi-stromal organoid co-cultures, highlighting disease-specific heterogeneity.
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Excessive contractility in embryos from aged females causes implantation failure, with a 100% link observed in mouse models.
Circadian oscillations in circulating tumour-derived extracellular vesicle abundance and function influence targeted therapy outcomes in mouse tumour models.
Long-lived intron-retained RNAs at nuclear speckle periphery are regulated during mitosis, with 20% of transcripts involved in genome maintenance and mitosis.
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Ribosome and mRNA concentrations scale proportionally with growth rate, enabling eukaryotic cells like Saccharomyces cerevisiae to accelerate proliferation efficiently.
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Moving areas, week to 3 Oct 2026
- Single-cell and spatial transcriptomics10
- Artificial Intelligence in Healthcare and Education8
- CAR-T cell therapy research7
- Neuroinflammation and Neurodegeneration Mechanisms6
- Lung Cancer Treatments and Mutations5
- Diabetes Treatment and Management4
- Pancreatic and Hepatic Oncology Research4
- Photosynthetic Processes and Mechanisms4
- Genomics and Chromatin Dynamics4
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