Research area · week to 3 Oct 2026

Global Cancer Incidence and Screening

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Cancer Diagnostic Delay Rates Associated With a Population-Based Screening Trial Evaluating a Cell-Free DNA Multicancer Early Detection Test.
JAMA · 14 July 2026 · Multicenter Study
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Shaping the future of early-onset colorectal cancer prevention.
Nature Reviews Cancer · 1 Oct 2026 · Review
Early-onset colorectal cancer (EOCRC) cases under age 50 are rising globally, with lifestyle and early-life factors contributing to the increasing burden.
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An LLM-Based Auditing Framework for Targeted Quality Assurance in Cancer Registries
medRxiv · 26 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.22.26363595
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Extracting smoking history from clinical notes for lung cancer screening decision support: comparing a structured-judgment model with general-purpose large language models
medRxiv · 26 Sept 2026 · Preprint
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Effectiveness of a Community-Based Cervical Cancer Stigma Reduction Intervention on Cancer Stigma and Cervical Cancer Screening Uptake in Nepal: A Cluster-Randomized Controlled Trial
medRxiv · 25 Sept 2026 · Preprint
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Developing cancer-control policies to address the cancer burden among young adults.
Nature Medicine · 24 Sept 2026 · Letter
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Trends and differences in breast cancer mortality by race, region and age among Brazilian women, 1996-2024: a nationwide ecological study
medRxiv · 23 Sept 2026 · Preprint
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Effect of Screening with Multicancer Early-Detection Test on Late-Stage Cancer Diagnosis.
New England Journal of Medicine · 22 Sept 2026 · Journal Article
Multicancer early-detection blood tests did not significantly reduce stage III or IV cancer incidence after three screening rounds in a large trial of over 142,000 participants.
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Performance and safety of a multi-cancer early detection test: the PATHFINDER 2 study.
Nature Medicine · 22 Sept 2026 · Journal Article
The PATHFINDER 2 study found that a blood-based multi-cancer early detection test achieved a cancer detection rate of 0.54% with high specificity and positive predictive value in adults aged 50 and older.
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Performance of a multi-cancer early detection test in the randomized controlled NHS-Galleri trial.
Nature Medicine · 22 Sept 2026 · Journal Article
The multi-cancer early detection test demonstrated a positive predictive value of up to 58% and detected primary cancers in 0.60% to 0.41% of participants across three screening rounds in NHS screening.
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Precision prevention and early detection: framework for a new clinical cancer control pathway.
The Lancet · 18 Sept 2026 · Review
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Breast cancer: Life extending drug is now available on NHS in England.
BMJ · 17 Sept 2026 · Journal Article
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The Association between Marital Status and Suicide Risk Among Patients with Breast Cancer A Population-Based sIPTW Competing Risk Analysis
medRxiv · 7 Sept 2026 · Preprint
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Interventions for Increasing Colorectal Cancer Screening Uptake: A Systematic Review and Network Meta-Analysis.
Gastroenterology · 1 Sept 2026 · Systematic Review
Patient navigation and mailed FIT outreach significantly increase colorectal cancer screening uptake, especially in populations with low baseline rates, with risk ratios of 1.58 and 1.36 respectively.
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Global breast cancer survival estimates in 2017-2021 to advance the WHO Global Breast Cancer Initiative.
Nature Medicine · 1 Sept 2026 · Journal Article
Global 5-year breast cancer survival rates from 2017-2021 ranged from 39.1% in Africa to 88.5% in the Americas, highlighting significant regional disparities.
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Rethinking Screening Paradigms: 13-Year NordICC Data Comparing Colonoscopy to No Screening Show Reduction in Colorectal Cancer Incidence but Not Mortality.
Gastroenterology · 7 Aug 2026 · Journal Article
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