Surveillance Mammography and Second Primary Breast Cancer Diagnosis Among Older Women With a History of Breast Cancer.

Continued surveillance mammography after nonmetastatic breast cancer in women aged 67+ is not linked to a lower risk of advanced second primary breast cancer (1.65% vs 2.15%).

• Why it matters: It is uncertain whether routine surveillance mammography in older survivors improves clinically meaningful outcomes, especially cancer stage at diagnosis.
• What they did: In a retrospective SEER-Medicare cohort of 9888 women diagnosed in 2004–2008 and followed after a surveillance mammogram at about 5 years, cause-specific hazard models with inverse probability of treatment weighting estimated stage-specific second cancer risk.
• The result: Advanced second primary breast cancer incidence did not differ between continued surveillance and no continued surveillance (hazard ratio 0.76; 95% CI 0.46–1.26), with similar findings by initial hormone receptor status.

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