CaZAT11, a nuclear-localized C2H2 zinc-finger protein, enhances cold tolerance in pepper by interacting with CaSTOP1 and regulating cold-responsive genes.
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Ion Channels and Receptors
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Mutations in the intracellular subdomain of LRRC8A cause constitutive activation of VRAC channels, highlighting its role as a key regulatory hub.
- Open access
- 1 cites
LRRC8A/D heteromeric channels are activated by cell swelling and modulated by sybodies, with a specific structure of four A and two D subunits revealing key conformational states.
- Open access
PRRT2 enhances Nav channel slow inactivation and delays recovery, affecting neuronal excitability from zebrafish to humans.
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Lamprey KCNE0, an early-diverging KCNE family member, induces constitutive KCNQ1 activity, highlighting its unique role in vertebrate ion channel regulation.
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