S. aureus grown in milk shows 10-fold higher resistance to reactive oxygen species and increased antimicrobial tolerance compared to serum-grown bacteria.
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Communications Biology
Nature Portfolio · Cell & Molecular Biology · ISSN 2399-3642
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High-resolution GWAS of nearly 600,000 East Asians reveals 196 loci for type 2 diabetes, with 3 new loci and 74% shared causal signals across populations.
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Cryo-EM reveals that native human CENP-A nucleosomes form octamers with distinct homotypic and heterotypic structures, crucial for centromere identity.
The thermodynamic state map of biomolecular condensates reveals how cellular inputs and molecular interactions govern phase behavior, enabling targeted modulation of material states.
Repurposed arthritis models reveal key features of chikungunya virus-induced joint inflammation, advancing understanding of this neglected pathology.
Recurrent euchromatic deletions on the Y chromosome in male cancers are linked to altered gene regulation and clinical outcomes, highlighting their functional significance.
A new protocol enables reliable culture and transcriptome profiling of human Schwann cells from small sural nerve biopsies, facilitating PNP research.
- Open access
The transactivation domain (TAD) is essential for nuclear import of phosphorylated STAT5, with two key residues D754 and D758 critical for this process.
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Clathrin adaptors Ent5 and Sla2 drive phase separation essential for membrane trafficking, with Ent5's helix and Sla2's coiled-coil mediating condensate formation.
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Coral-associated denitrification varies seasonally and species-specifically, with rates up to 2.0 nmol N cm−2 h−1 in Dendrophylliidae indet corals.
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Fermented protein foods may influence skeletal muscle health through the gut-muscle axis, but direct evidence on muscle outcomes remains limited despite promising preliminary findings.
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Cyclic thermal stress during pupation causes up to 30% pupal mortality and halves adult longevity in Bombus terrestris, threatening pollinator resilience.
Actin conformation changes in cytotoxic T lymphocytes occur before force generation during migration and killing, highlighting a regulatory role in immune responses.
Mitochondrial heterogeneity creates a dynamic organelle ecosystem with diverse subpopulations differing in form and function, impacting cellular physiology and disease.
Coinfecting haloarchaeal viruses Tebi-SV1 and Tebi-PV1 interact symbiotically, with Tebi-PV1 regulating Tebi-SV1 abundance through shared genetic elements.
Weevil species exhibit highly variable plant cell wall-degrading enzyme repertoires that correlate with their feeding ecology, driven by gene transfer, duplication, and loss.
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Streptococcus pyogenes nuclease A inhibits complement activation by preventing membrane attack complex assembly, revealing a novel immune evasion mechanism.
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A human cell-free translation screen identified NT-2 as a novel ribosomal inhibitor binding the peptidyl transferase center, disrupting mammalian protein synthesis.
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Increased reliance on higher-level linguistic processing compensates for age-related decline in attentional filtering during multitalker speech comprehension, especially in older adults.
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Plant-derived pectin forms distinct nanoscale morphologies and tightly associates with animal tissue, demonstrating potential as a bioadhesive in lung surgery.
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Microfluidic and organ-on-chip technologies enable detailed study of bacteria-host interactions and tumor microenvironments, revealing new insights into microbiology and cancer therapy.
Tailored and shielded LED road lights reduce insect attraction most effectively during peak nocturnal activity hours, with limited impact during twilight and late night.
Unconventional protein secretion offers new design principles to enhance rapid control of extracellular protein release in mammalian cells.
- Open access
Spatial proteomics reveals FXYD6 as a dual-site protein at the neuromuscular junction in the diaphragm, with significant enrichment in type IIa fibers.
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N4BP1 uses tandem KH domains to bind EDC4 and decapping factors, regulating mRNA decay and viral transcripts in P-bodies.
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The Soifua Manuia reference panel with 2,570 Samoan haplotypes doubles the number of well-imputed variants compared to TOPMed-R3 and 1KGP in Samoans.
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YAP1 induces hepatocellular carcinoma through DNA demethylation, not canonical driver gene mutations, with widespread demethylation activating oncogenes in mouse models.
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Cochlin, an extracellular matrix protein, enhances brain immune defense by reducing bacterial load, with levels increasing during infection in zebrafish, mice, and humans.
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- Lancet149
- Science138
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Moving areas, week to 3 Oct 2026
- Single-cell and spatial transcriptomics10
- Artificial Intelligence in Healthcare and Education8
- CAR-T cell therapy research7
- Neuroinflammation and Neurodegeneration Mechanisms6
- Lung Cancer Treatments and Mutations5
- Diabetes Treatment and Management4
- Pancreatic and Hepatic Oncology Research4
- Photosynthetic Processes and Mechanisms4
- Genomics and Chromatin Dynamics4
- Gut microbiota and health4