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Circadian rhythm and melatonin

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Latest in Circadian rhythm and melatonin

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Beyond Calorie Counting: Is Circadian Alignment Key to Metabolic Health in Crohn's Disease?
Gastroenterology · 1 Oct 2026 · Letter
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Beyond heatwaves and cold spells: Long-term exposure to short-duration extremes, behavioural pathways, and hypertension risk in a national Chinese cohort.
Environmental research · 1 Oct 2026 · Journal Article
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Independent and interactive effects of personal light exposure and air pollution on incident COPD: A prospective cohort study with 13 million hours of light sensor data.
Environmental pollution · 1 Oct 2026 · Journal Article
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Prenatal exposure to outdoor artificial light at night and neonatal thyroid function: Identifying critical windows of susceptibility.
Environmental pollution · 1 Oct 2026 · Journal Article
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Time matters: circadian genetics and the molecular logic of human health and disease.
Nature Reviews Genetics · 1 Oct 2026 · Review
Genetic variation and misalignment of the circadian clock significantly influence human health, disease risk, and treatment outcomes, highlighting the importance of temporal biology.
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Diurnal differences in the effects of heat exposure on renal function: A randomized controlled crossover trial.
Environmental research · 1 Oct 2026 · Randomized Controlled Trial
Heat exposure causes distinct diurnal renal responses, with daytime exposure affecting blood markers and nighttime exposure elevating urinary stress biomarkers, highlighting time-dependent kidney vulnerability.
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Dietary Restriction Impacts Peripheral Diurnal Rhythms Important for Longevity in Drosophila
bioRxiv · 28 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2023.01.04.522718
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Directed effective connectivity between the SCN-containing hypothalamus and pineal gland varies by chronotype in bipolar disorder
medRxiv · 26 Sept 2026 · Preprint
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Remodeling of the hepatic circadian transcriptome across the estrous cycle.
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.22.733912
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Circadian syndrome and incident non-neoplastic digestive disease in middle-aged and older Chinese adults: a prospective cohort study
medRxiv · 25 Sept 2026 · Preprint
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Integrated respirometry and metabolomics unveil circadian metabolic dynamics in Drosophila.
eLife · 24 Sept 2026 · Journal Article
Circadian and sleep disruptions in Drosophila melanogaster cause significant metabolic dysregulation, with mutant and constant darkness conditions showing impaired redox homeostasis.
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Role of the pulvinar in early visual cortical signaling in the macaque.
Cell Reports · 23 Sept 2026 · Journal Article
The pulvinar primarily relays signals from V1 to V2 in macaques, with V1 activity leading pulvinar and pulvinar leading V2, supporting a feedforward communication role.
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Epigenetic characterization and manipulation of rare circadian neuron subtypes
bioRxiv · 21 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.01.21.700891
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Skin commensals shape the clock-ferroptosis axis to preserve barrier function in psoriasis.
Cell Reports · 17 Sept 2026 · Journal Article
Lactobacillus plantarum and its metabolite indole-3-lactic acid restore skin barrier function by modulating the clock-ferroptosis axis in psoriasis.
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Anticipatory metabolic regulation drives the distinct and improved metabolic state of caloric restriction compared to Fasting-Refeeding cycles.
Cell Reports · 17 Sept 2026 · Journal Article
Caloric restriction enhances circadian metabolic regulation and improves glucose and fatty acid metabolism compared to fasting-refeeding cycles, with a significant impact on metabolic health.
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A population of dopaminergic neurons in the substantia nigra is required for food-anticipatory activity.
Current Biology · 17 Sept 2026 · Journal Article
Deletion of tyrosine hydroxylase in approximately 25% of substantia nigra dopamine neurons significantly reduces food-anticipatory locomotion in mice.
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Tissue-wide Erk oscillations set the pace of zebrafish notochord segmentation
bioRxiv · 17 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.08.28.672946
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Minimum Grid Cells for Place Cell Activity in Eleven Enclosures
bioRxiv · 16 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.11.15.623794
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Sex-specific biological aging clocks across organs and omics.
Nature Medicine · 16 Sept 2026 · Journal Article
Sex-specific biological aging clocks across organs reveal distinct genetic, molecular, and clinical aging signatures in males and females.
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Long-term outdoor artificial light at night and psychological symptoms among Chinese adolescents: Findings from a national school-based survey.
Environmental research · 15 Sept 2026 · Journal Article
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Long-term exposure to air pollution, proteomic aging clocks, and liver-related outcomes in Chinese adults.
Environmental research · 15 Sept 2026 · Journal Article
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Subchronic PM(2.5) exposure exacerbates chronic stress-induced depression-like pathology in mice.
Environmental research · 15 Sept 2026 · Journal Article
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Human-Specific Regulation of CHD2 Controls the Tempo of Cortical Development through Lysosomal Homeostasis
bioRxiv · 14 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.01.21.634145
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An automated genetic screen identifies modulators of stress-induced sleep in Caenorhabditis elegans
bioRxiv · 12 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.16.725661
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Pluripotency and Transcriptional Pausing Disrupt Circadian Rhythms to Facilitate the Enrichment of Cancer Stem Cells
bioRxiv · 11 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.10.737844
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The hypoxic response extends lifespan through a bioaminergic and peptidergic neural circuit.
bioRxiv · 11 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.05.04.652087
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Feature Selectivity for Circadian Regulation within Melanopsin Photoreceptors
bioRxiv · 10 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2025.12.30.695276
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Neocortical long-range inhibition promotes cortical synchrony and sleep.
Nature · 9 Sept 2026 · Journal Article
Long-range Sst-Chodl inhibitory neurons in the neocortex actively promote sleep and synchronized cortical activity, especially during low-arousal states, in mice.
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Cortical layer 6b mediates state-dependent changes in brain activity and effects of orexin on waking and sleep.
eLife · 8 Sept 2026 · Journal Article
Silencing cortical layer 6b in mice reduces EEG power and slows brain oscillations during wake and REM sleep, highlighting its role in brain state regulation.
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Glucocorticoid rhythm disruption drives hyperinsulinaemia in mice through beta cell glucocorticoid receptor signalling
bioRxiv · 6 Sept 2026 · Preprint
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