Research area · week to 3 Oct 2026

3D Printing in Biomedical Research

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Phenotypes and Cellular Mechanics of Primary Human Aorta- and Pluripotent Stem Cell-derived Vascular Smooth Muscle Cells
bioRxiv · 2 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2025.12.18.694995
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Restoring intracellular homeostasis disrupted by synthetic nanoassemblies.
Nature Chemical Biology · 1 Oct 2026 · Journal Article
Programmable nanoassembly cycles restore bacterial redox and energy balance by linking supramolecular transformations with genetic responses.
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https://jclub.com.au/a/42469449
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Lung-mimicking click alginate-dECM model of breast cancer lung metastasis reveals the role of ECM mechanics in tumor growth dynamics and genomic instability
bioRxiv · 27 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.01.08.698349
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Stimulatrix: An open-source automated platform for high-throughput functional characterization of engineered contractile tissues
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.24.750079
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Modular engineered colorectal tumor microenvironments for immuno-oncology research and drug development
bioRxiv · 23 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.02.729459
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Multi-omics analyses reveal environmentally adaptive cell-state remodeling during human iPSC biomanufacturing
bioRxiv · 21 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.26.727850
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A world model of the virtual cell.
Cell · 17 Sept 2026 · Review
A virtual cell world model (VCWM) enables dynamic, long-term simulation of cellular behavior, supporting complex interventions and biological discovery.
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https://jclub.com.au/a/42753692
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Physicochemical balancing facilitates fast cyclic immunolabeling in centimeter-scale FFPE tissues
bioRxiv · 17 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.03.09.710440
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Reverse bioengineering of the liver: developmental principles for next-generation liver-on-a-chip systems.
Communications Biology · 16 Sept 2026 · Review
Reverse bioengineering of liver-on-a-chip systems reveals developmental principles that outperform current models, with 80% of key developmental features captured.
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https://jclub.com.au/a/42749751
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Contractile to extensile transitions and mechanical adaptability enabled by activity in cytoskeletal structures
bioRxiv · 10 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.02.22.581411
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Towards 3D-oid models that integrate molecular, morphological and spatial cellular features.
Nature Reviews Molecular Cell Biology · 4 Sept 2026 · Journal Article
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https://jclub.com.au/a/42698024
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Effect of human urinary microenvironment and fluid flow on antibiotic and phage therapy efficacy against uropathogenic Escherichia coli.
Nature Communications · 4 Sept 2026 · Journal Article
Microenvironmental factors in the human urinary system significantly reduce the effectiveness of antibiotics and phages against uropathogenic Escherichia coli, especially under flow conditions.
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Left-Right Asymmetry in the Breast TME is Associated with Distinct Bioelectric and Epigenetic Tumor Features.
bioRxiv · 3 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.06.30.662430
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Selective organ deposition of nanoparticles directed by metal-organic network coatings.
Nature Communications · 2 Sept 2026 · Journal Article
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https://jclub.com.au/a/42823437
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5 perspectives on translating microphysiological systems from concept to application.
Nature Communications · 27 Aug 2026 · Interview
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https://jclub.com.au/a/42660932
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Spatially patterned cytoskeletal organization shapes astrocyte branch complexity
bioRxiv · 23 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.10.10.681734
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Human Cytomegalovirus Infects and Remodels 3D-biofabricated Skin Equivalents
bioRxiv · 22 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.08.21.746345
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Six-compound cocktail for maturation of human pluripotent stem cell-derived liver spheroids for toxicity prediction.
Nature Communications · 21 Aug 2026 · Journal Article
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Glioblastoma - Neuroblastoma co-cultured multicellular spheroid model for evaluating Temozolomide response
bioRxiv · 20 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.11.11.622957
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Interplay Between Base Editing and DNA repair: From Molecular Mechanisms to Clinical Translation.
Biotechnology advances · 18 Aug 2026 · Review
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https://jclub.com.au/a/42612929
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CFM: Confinement Force Microscopy-a dynamic, precise and stable microconfiner for traction force microscopy in spatial confinement
bioRxiv · 10 Aug 2026 · Preprint
Confinement Force Microscopy reveals two-phase cellular stress response to dynamic spatial confinement, with a 2-stage increase in traction forces during migration.
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https://jclub.com.au/a/10.1101/2023.08.22.554088
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Photoinitiator-free visible-light bioprinting: minimising radical-induced oxidative stress and DNA damage in gelatin hydrogels
bioRxiv · 6 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2025.12.01.691472
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Heterotypic interfacial tension between oncogenic and wild-type populations forms the mechanical basis of tissue-specific oncogenesis in epithelia.
eLife · 6 Aug 2026 · Journal Article
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https://jclub.com.au/a/42559715
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In situ particle-to-fibre transformation of hydrogels for 3D printing.
Nature · 5 Aug 2026 · Journal Article
Shear-extensional in situ particle-to-fibre transformation (SHIFT) enables the creation of highly aligned hydrogel microfibres with pronounced anisotropy, achieving diameters of 5-30 μm.
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https://jclub.com.au/a/42557327
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Spatial control of light-responsive proteins and optogenetics within hydrogels via volumetric bioprinting
bioRxiv · 5 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.09.717404
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