Intratumoral T cell activation can eradicate tumors without tumor-specific T cell receptors, relying on paracrine signaling and innate immune responses.
Immune Cell Function and Interaction
Moving in bioRxiv, Nature Immunology, Blood, Nature, Cell Reports, eLife, Nature Cell Biology, Cancer Discovery.
- Moved this week
- 0
Rebuilt
Moved this week
Nothing in this area has moved yet this week.
Latest in Immune Cell Function and Interaction
Newest first · last 60 days
HnRNPK limits memory B-cell and plasma cell differentiation, maintaining germinal center B-cell output by regulating transcription and metabolism.
Monocyte-derived galectin-1(hi) cells are essential for generating and maintaining lung tissue-resident memory CD8+ T cells after influenza infection, with over 4 months persistence.
- 1 cites
Targeting ZMYND8 enhances IL-2 signaling, promoting effector-like CD8+ T cell responses and improving antiviral and antitumor immunity.
- Open access
A novel Fab-dimerized glycan (FDG) antibody with a dual-glycan clamp epitope was isolated, showing approximately 30% breadth against HIV-1 and unique architecture.
- Open access
DGKα and ζ deficiency in regulatory T cells causes their destabilization and conversion to pathogenic Tfh cells, triggering IgG1-predominant autoimmunity.
- Open access
- 1 cites
MAIT cells exhibit tissue-dependent responses to S. aureus and show variable sensitivity to HlgAB toxin, with tonsillar MAIT cells being notably resistant.
- Open access
Mature NK cell subsets with varying proliferative abilities generate stochastic clonal heterogeneity during early MCMV response, driven by proliferation and cell death dynamics.
- Open access
BHLHE40 orchestrates intestinal immunity by regulating ILC3s and RORγt⁺ APCs, crucial for mucosal defense and tolerance, with a 40-fold increase in expression during inflammation.
- Open access
Allogeneic BCMA CAR T cells armed with NKG2A receptor (CT0590) effectively resist host NK cell attacks and show durable responses in multiple myeloma patients.
Lactate-α-ketoglutarate metabolic circuit in tumor-infiltrating Treg cells promotes tumor progression by inducing NK cell senescence, with GDH1 as a key driver.
Dysbiosis-induced expansion of AXL-positive inflammatory type 3 dendritic cells drives preclinical autoimmunity in mice, linking gut microbes to systemic autoimmune features.
- Open access
Restoring mitochondrial complex I activity via NDUFA9 enhances natural killer cell function, improving immunotherapy outcomes in glioblastoma patients.
Follow this area in the app
Browse JClub
Journals this month
- bioRxiv5569
- medRxiv1746
- Environ Res485
- PNAS463
- Sci Adv439
- JAMA255
- Cell Rep210
- BMJ205
- Nat Commun177
- Environ Pollution170
- Lancet149
- Science138
- NEJM119
- Applied & Environ Microbio116
- Curr Biol116
- J Exp Bot115
- mBio109
- Nature104
Moving areas, week to 3 Oct 2026
- Single-cell and spatial transcriptomics10
- Artificial Intelligence in Healthcare and Education8
- CAR-T cell therapy research7
- Neuroinflammation and Neurodegeneration Mechanisms6
- Lung Cancer Treatments and Mutations5
- Diabetes Treatment and Management4
- Pancreatic and Hepatic Oncology Research4
- Photosynthetic Processes and Mechanisms4
- Genomics and Chromatin Dynamics4
- Gut microbiota and health4