Nature Cancer
Nature Portfolio · Oncology · ISSN 2662-1347
- Impact (2-yr)
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- Open access
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- Papers this month
- 11
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Latest in Nat Cancer
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Stroke promotes glioma progression by inducing tumor-associated astrocytes with reduced Ca(2+) activity, leading to decreased survival in human and mouse models.
Complex mutational phenomena in human cancers exhibit diverse patterns, with at least eight distinct types identified over 15 years, impacting tumor evolution and clinical outcomes.
An iron-dependent methionine redox pathway controls adipose browning and cachexia, with MsrA deletion reducing cachexia and extending survival in mouse models.
- Open access
- 1 cites
CROWN achieves over 95% accuracy in 48 cytology classification tasks, establishing a universal visual backbone for computational cytopathology.
Circulating tumor DNA-guided therapy in high-risk colon cancer achieved a 2-year relapse-free rate of 88% in ctDNA-negative patients, but did not meet the predefined threshold.
- Open access
MMSDH-driven ACSL4 propionylation promotes ferroptosis evasion, reducing chemotherapy effectiveness in hypoxic pancreatic cancer by 50%.
Commensal Nakaseomyces glabratus translocates from the gut to prostate tumors, accelerating cancer progression and worsening patient survival in castration-resistant prostate cancer.
- Open access
Galanin promotes immunosuppression and ferroptosis resistance in glioblastoma by enhancing myeloid-derived suppressor cell infiltration, leading to immunotherapy resistance in mouse models.
In vivo CAR T cell engineering can directly generate therapeutic T cells within patients, potentially overcoming manufacturing barriers and expanding access to cancer treatment.
Lactate-α-ketoglutarate metabolic circuit in tumor-infiltrating Treg cells promotes tumor progression by inducing NK cell senescence, with GDH1 as a key driver.
Fc-optimized human GITR antibody boosts antitumor immunity by enhancing CD4 T cell and dendritic cell interactions, achieving superior therapeutic effects.
- Open access
Targeting PID1 in tumor-associated macrophages produces oxysterols that reprogram macrophages toward an antitumor phenotype, enhancing immune responses in multiple cancers.
F-actin-FcγR bridging enhances anticancer immunity by redirecting abundant tumor-associated APCs to cross-present necrotic tumor antigens, improving tumor control in mouse models.
- Open access
SlideChat achieves a 19.1% higher accuracy in interpreting gigapixel-scale whole-slide images across 31 cancer types, outperforming existing models in computational pathology.
Adding L-glutamine to gemcitabine and nab-paclitaxel nearly doubled the overall survival to 22 months in advanced pancreatic ductal adenocarcinoma patients.
- Open access
Low-protein diet boosts antitumor immunity in pancreatic cancer by increasing microbiota-derived UDP-galactose, reducing tumor progression in mice.
VINCENT, a TIM3-targeted nanoformulation, overcomes venetoclax resistance and reactivates NK cells in AML, showing efficacy in resistant models and patient samples.
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Journals this month
- bioRxiv5569
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- Environ Res483
- PNAS463
- Sci Adv439
- JAMA255
- Cell Rep210
- BMJ199
- Nat Commun177
- Environ Pollution170
- Lancet149
- Science138
- NEJM119
- Applied & Environ Microbio116
- J Exp Bot115
- Curr Biol112
- mBio109
- Nature104
Moving areas, week to 3 Oct 2026
- Single-cell and spatial transcriptomics10
- Artificial Intelligence in Healthcare and Education8
- CAR-T cell therapy research7
- Neuroinflammation and Neurodegeneration Mechanisms6
- Lung Cancer Treatments and Mutations5
- Diabetes Treatment and Management4
- Pancreatic and Hepatic Oncology Research4
- Photosynthetic Processes and Mechanisms4
- Genomics and Chromatin Dynamics4
- Gut microbiota and health4