Neurogenesis and neuroplasticity mechanisms
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Latest in Neurogenesis and neuroplasticity mechanisms
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Mapping the mouse brain lipidome reveals a detailed biochemical architecture with significant spatial heterogeneity across regions and conditions.
- Open access
- 1 cites
A human iPSC-derived spheroid model reveals that remyelinated axons have thinner myelin sheaths after injury, advancing understanding of human myelin repair mechanisms.
- Open access
Oligodendrocytes actively support CNS function and contribute to disease, with their heterogeneity influencing roles across development, aging, and pathology.
Single-cell APA profiling in 2 million human brain cells reveals cell-type-specific genetic regulation linked to neurodegenerative diseases, including Alzheimer’s and Parkinson’s.
- Open access
Massively parallel reporter assay reveals 918 regulatory variants linked to human cortical structure, with over half showing allelic effects and some being condition-dependent.
- Open access
NFIs act as conserved global temporal regulators of radial glial progenitor development, with mutations causing bidirectional impairments linked to human neocortical malformations.
Self-organizing human dual neural organoids (hPCOs) reveal Wnt signaling's bidirectional role in central and peripheral nervous system development, modeling key disease defects.
A miR-10a-5p-γCaMKII axis mediates peripheral signals that increase brain vulnerability during female midlife, with miR-10a-5p levels rising significantly in this period.
Two distinct neural ectoderm progenitors independently generate the forebrain/midbrain and hindbrain regions in mouse and human development.
- 1 cites
Transcriptome analysis of 17 ASD-risk mouse lines reveals two opposing molecular states with distinct sex, regional, and developmental features.
- 1 cites
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