The abstract is read at the publisher; the summary is JClub's.
From day 2 to later days in human intracranial recordings, hippocampal–neocortical ripple coupling strengthens and reverses sequence from hippocampus-leading to neocortex-leading.
- Why it matters: Systems consolidation depends on hippocampal–neocortical interplay, but its day-by-day evolution during repeated learning and recall is unclear.
- What they did: Subjects completed a repeated picture-learning task while day-by-day multisite intracranial electrophysiology measured ripple rates during picture learning and free recall.
- The result: Ripple rates increased from day 1 to day 2 in both hippocampus and neocortex, correlated with memory performance, and coupling enhancements persisted across remaining days.
The findingWhy it mattersWhat they didThe result
AI summary of the abstract · may contain errors · not medical advice · read the paper.