3D DNA walkers enable highly sensitive biosensors with programmable movement for detecting foodborne pathogens, advancing food safety monitoring.
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Advanced biosensing and bioanalysis techniques
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Proteolytic control of CRISPR-Cas systems achieves precise, tunable gene expression with reduced variability, enabling improved gene therapy for dosage-sensitive disorders.
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VIPR systems achieve precise DNA targeting through noncontiguous triplex formation, with 21 cryo-EM structures revealing the mechanism of target engagement.
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Intercellular transfer of DNA via nanotubes occurs in human cells, with over 50% of transfer events resulting in functional DNA integration into recipient nuclei.
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