Research area · week to 3 Oct 2026

Mosquito-borne diseases and control

Moving in mBio, New England Journal of Medicine.

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Bundibugyo Virus Disease in 2026 - Clinical and Public Health Responses.
New England Journal of Medicine · 16 July 2026 · Review
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https://jclub.com.au/a/42341299
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Single-cell analysis of Powassan virus-infected brains reveals age-dependent neuroinflammatory crosstalk and progressive Alzheimer's-like APP/Aβ accumulation.
mBio · 12 Aug 2026 · Journal Article
Powassan virus infection causes age-dependent neuroinflammation and persistent Alzheimer’s-like APP/Aβ accumulation in mouse brains, with 50-week-old mice showing significant neurodegenerative changes.
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https://jclub.com.au/a/42446869
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Remodeling of sporozoite microtubules during Plasmodium liver stage development
bioRxiv · 2 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.06.26.661843
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Andes Virus - A Clinical Review.
New England Journal of Medicine · 1 Oct 2026 · Review
Andes virus (ANDV) is the only orthohantavirus known to transmit between humans, posing unique challenges for disease control and management.
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A generalized lineage nomenclature for viral genomic epidemiology.
Nature Microbiology · 30 Sept 2026 · Journal Article
A generalized lineage nomenclature system enables scalable viral genomic surveillance, exemplified by defining 21 chikungunya virus lineages across 8 founding lineages.
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https://jclub.com.au/a/42816583
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Spatial patterns of mosquito communities and monkey malaria vectors in a tropical riverine forest in Sabah, Malaysian Borneo
bioRxiv · 28 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.27.720977
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Potency of nucleoside analogs against Powassan virus replication and identification of 4'-fluorouridine as a therapeutic candidate for tick-borne orthoflavivirus encephalitis
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.24.754293
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Long term rescue of Alzheimer deficits in vivo by one-time gene-editing of App C-terminus.
bioRxiv · 22 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.06.08.598099
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Longitudinal dynamics and lineage cross-reactivity of the human antibody response to West Nile virus.
mBio · 17 Sept 2026 · Journal Article
WNV infection induces durable neutralizing antibodies with a half-life of up to 472 days, but cross-reactivity against divergent lineages varies significantly among individuals.
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https://jclub.com.au/a/42752195
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Reproductive isolation and structural variation among sympatric lineages of an international mosquito pest
bioRxiv · 14 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.10.717866
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Global determinants of vector-targeted insecticide use in public health: a modeling and mapping analysis
medRxiv · 12 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.08.26350404
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Sub-national heterogeneity in the time-varying reproduction number during the 2026 Bundibugyo virus disease outbreak in the Democratic Republic of the Congo: a hierarchical Bayesian analysis
medRxiv · 11 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.08.19.26360792
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Febrile temperature enhances Plasmodium falciparum and neutrophil adhesion by disrupting the endothelial glycocalyx
bioRxiv · 10 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.09.07.674757
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Genomic analysis identifies candidate supergene architecture for host-feeding behavior in wild Aedes aegypti dengue vector mosquitoes.
Frontiers in Genetics · 9 Sept 2026 · Journal Article
Genomic analysis reveals a potential supergene architecture associated with human host-feeding behavior in Aedes aegypti mosquitoes, involving a specific inversion on chromosome 2.
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https://jclub.com.au/a/42775097
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Targeting Dengue Virus NS3 Helicase: Biochemical and Computational Evaluation of Catechins from Camellia sinensis as Potential Therapeutic Leads
bioRxiv · 3 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.22.733882
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Genomic Epidemiology of CHIKV During the Largest Outbreak in Mainland China-Implication for CHIKV Intervention
medRxiv · 2 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.16.26355213
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Coupling experiments and macroecological models to resolve multi-stressor effects in vector-pathogen systems.
Nature Reviews Microbiology · 1 Sept 2026 · Journal Article
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https://jclub.com.au/a/42332288
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Reframing risk assessment for malaria elimination in a changing climate.
Nature Reviews Microbiology · 1 Sept 2026 · Journal Article
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https://jclub.com.au/a/42342965
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Impacts of climate change on dengue.
Nature Reviews Microbiology · 1 Sept 2026 · Journal Article
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https://jclub.com.au/a/42286204
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Climate adaptation and biodiversity shape West Nile virus risk in cities.
Nature Reviews Microbiology · 1 Sept 2026 · Journal Article
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https://jclub.com.au/a/42393425
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A small molecule inhibits Ebola virus entry through glycoprotein stabilization.
Nature Communications · 1 Sept 2026 · Journal Article
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https://jclub.com.au/a/42816550
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Evidence of thermal selection from experimental evolution in the arboviral vector Aedes albopictus
bioRxiv · 28 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.22.727092
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Yellow fever re-emergence in Tolima, Colombia 2024-25: an eco-epidemiological study
medRxiv · 27 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.01.16.26344301
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Tracking West Nile virus dynamics using viral loads from trapped mosquitoes
bioRxiv · 26 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.07.02.662782
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N-linked glycosylation of GETV envelope proteins affect viral infection and pathogenicity.
Virulence · 26 Aug 2026 · Journal Article
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https://jclub.com.au/a/42625313
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Gcn5 and mTORC1 mediated regulation of autophagy controls Drosophila blood cell homeostasis
bioRxiv · 25 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2023.07.04.547637
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Post-exposure prophylaxis with a monoclonal antibody cocktail after Bundibugyo ebolavirus exposure in adults and children.
Nature Medicine · 24 Aug 2026 · Journal Article
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https://jclub.com.au/a/42742181
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A case of Bundibugyo virus disease treated with monoclonal antibodies and remdesivir.
Nature Medicine · 24 Aug 2026 · Journal Article
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https://jclub.com.au/a/42742180
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WITHDRAWN: A Comprehensive Hybrid Capture Sequencing Platform for Tick-borne Disease Detection Reveals Zoonotic Emerging Pathogens in a Weather and Vector Transition Zone
bioRxiv · 24 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.06.08.658352
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Coupling models of within-human, human-to-mosquito, and within-mosquito malaria parasite dynamics to identify key drivers of malaria transmission
medRxiv · 24 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.10.28.25339021
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Field-isolate recombinant tick-borne encephalitis viruses define reporter-stability guidelines for antiviral testing in flaviviruses
bioRxiv · 21 Aug 2026 · Preprint
Recombinant tick-borne encephalitis viruses with stable reporter genes enable effective antiviral testing, with Nluc showing superior stability over eGFP in diverse cell types.
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https://jclub.com.au/a/10.64898/2026.02.23.707037
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Structural and mechanistic insights into protective non-neutralizing antibodies targeting Crimean-Congo hemorrhagic fever virus nucleocapsid protein.
Nature Communications · 21 Aug 2026 · Journal Article
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https://jclub.com.au/a/42754559
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