Research area · week to 3 Oct 2026

HIV Research and Treatment

Moving in bioRxiv, medRxiv, Journal of hepatology, Nature Communications, Cell Reports, Communications Biology, eLife, mSystems.

Moved this week: 0

Rebuilt 3 October 2026 at 5:00 pm AEST

Moved this week

Everything that moved →

Nothing in this area has moved yet this week.

Latest in HIV Research and Treatment

Newest first · last 60 days

Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization.
eLife · 2 Oct 2026 · Journal Article
Gp41-directed antibodies neutralize HIV-1 by allosterically stabilizing or opening Env conformations, revealing two distinct modes of neutralization with long-range effects.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42826053
Open in JClub
Mechanisms of HIV-1 assembly, release and maturation.
Nature Reviews Microbiology · 1 Oct 2026 · Review
Advances in structural biology and imaging have revealed detailed mechanisms of HIV-1 assembly, release, and maturation, enabling targeted antiviral development.
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42277315
Open in JClub
Finishing the fight against HIV.
Nature Microbiology · 29 Sept 2026 · Editorial
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42811104
Open in JClub
Deconvolution of HIV-1 Mutational Signatures Reveals Dominant and Donor-Specific APOBEC3-Associated Mutagenesis Across Anatomical Compartments
bioRxiv · 25 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.09.23.753842
Open in JClub
Efficacy of postmenopausal estrogen replacement in SIV-infected female macaques on antiretroviral therapy.
bioRxiv · 25 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.09.21.746440
Open in JClub
Human CD34⁺ progenitor-derived DC2 and DC3 subsets support CD169-mediated HIV-1 uptake
bioRxiv · 25 Sept 2026 · Preprint
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.09.21.753077
Open in JClub
Stability of HIV RNA in plasma stored at different temperatures
medRxiv · 25 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.09.22.26363748
Open in JClub
An altered B cell compartment distinguishes low antibody responders among people with HIV
medRxiv · 23 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.09.18.26363407
Open in JClub
HIV-1 antibody-mediated neutralization via a dual-glycan clamp.
Cell Reports · 22 Sept 2026 · Journal Article
A novel Fab-dimerized glycan (FDG) antibody with a dual-glycan clamp epitope was isolated, showing approximately 30% breadth against HIV-1 and unique architecture.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42690933
Open in JClub
Structural basis of lenacapavir-induced HIV-1 capsid defects during virion maturation.
Nature Communications · 22 Sept 2026 · Journal Article
Lenacapavir disrupts HIV-1 capsid maturation by altering interhexamer interactions, preventing functional cone-shaped capsid formation during virion assembly.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42773142
Open in JClub
Evidence for multiple prion conformers in natural scrapie isolates.
PLOS Pathogens · 17 Sept 2026 · Journal Article
Multiple prion conformers coexist within single natural scrapie isolates, with at least one previously unrecognized conformer identified through enhanced detection methods.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42752506
Open in JClub
N4BP1 uses tandem KH domains to associate with EDC4 and mRNA decapping factors in P-bodies.
Communications Biology · 17 Sept 2026 · Journal Article
N4BP1 uses tandem KH domains to bind EDC4 and decapping factors, regulating mRNA decay and viral transcripts in P-bodies.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42754686
Open in JClub
Priming of Multiple HIV Neutralizing B Cell Precursors in Humans
medRxiv · 11 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.05.02.26352058
Open in JClub
Quantitative and amino acid sequence analysis of soluble HIV-1 Vpu and calmodulin interactions
bioRxiv · 7 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.04.15.718738
Open in JClub
Covalent anti-HIV compound that induces HIV-1 capsid multimerization and degradation, decomposes the viral core
bioRxiv · 2 Sept 2026 · Preprint
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.04.19.649630
Open in JClub
Atomic layer deposition for core-shell microparticle vaccines enabling programmable antigen delivery and enhanced humoral immune responses
bioRxiv · 2 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.05.29.728600
Open in JClub
Silent but persistent: Failure of continuous tenofovir based ART to prevent HBV and HDV reactivation under chemotherapy in an HBsAg-negative patient living with HIV.
Journal of hepatology · 2 Sept 2026 · Letter
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42685983
Open in JClub
Genomic Epidemiology of CHIKV During the Largest Outbreak in Mainland China-Implication for CHIKV Intervention
medRxiv · 2 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.06.16.26355213
Open in JClub
Reining in immune responses with MDM2.
Nature Cell Biology · 1 Sept 2026 · Journal Article
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42717244
Open in JClub
Design of optimized epigenetic regulators for durable gene silencing with application to PCSK9 in nonhuman primates.
Nature Biotechnology · 1 Sept 2026 · Journal Article
Optimized TALE-based epigenetic regulators achieve 98% gene silencing with durable effects over 343 days in primates.
- 5 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/41034497
Open in JClub
In vivo effect of anti-PD-1 on HIV-specific CD8+T-cells in men with HIV.
Nature Communications · 1 Sept 2026 · Journal Article
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42768041
Open in JClub
Serum HBsAg cannot distinguish cccDNA activity from integrated HBV DNA expression in chronic hepatitis B virus infection.
Journal of hepatology · 29 Aug 2026 · Journal Article
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42668120
Open in JClub
Sequential IL-15 and TGF-β1 stimulation expands reprogrammed CD103⁺CD39⁺ effector CD8⁺T cells and enhances HIV control
bioRxiv · 27 Aug 2026 · Preprint
Read the brief in JClub
- Open access
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.04.09.647906
Open in JClub
Larger inducible reservoir and higher abundance of exhausted CD8+ T cells in people treated after late versus non-late diagnosis of chronic HIV one year after ART initiation
bioRxiv · 26 Aug 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.03.31.715509
Open in JClub
Liver sinusoid constraints make random search of CD8 T cells for Plasmodium parasites efficient
bioRxiv · 25 Aug 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.10.11.681610
Open in JClub
Host Genetic Regulation of NLRP3 Inflammasome Cytokines Reveals Immune and Vascular Pathways in HIV
medRxiv · 24 Aug 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.06.08.26355202
Open in JClub
WITHDRAWN: Real-World Validation of Machine Learning Models for HIV Treatment Adherence Prediction and Care Gap Quantification: A Multi-Country Analysis of 192,732 Clinical Records
medRxiv · 21 Aug 2026 · Preprint
Read the brief in JClub
- Open access
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.05.15.26353325
Open in JClub
Ultra-deep duplex sequencing reveals unique features of somatic evolution in the normal tissues of a family with Li-Fraumeni syndrome
bioRxiv · 20 Aug 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.01.12.699071
Open in JClub
Population-level genome sequencing reveals distinct Mycobacterium tuberculosis intrahost mutational trajectories in simian immunodeficiency virus-coinfected and antiretroviral treated non-human primates.
mSystems · 18 Aug 2026 · Journal Article
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42505123
Open in JClub
An Optimized Product-Enhanced Reverse Transcriptase Assay for Sensitive and Quantitative Detection of HIV Viral Load and Phenotypic Drug Resistance
bioRxiv · 17 Aug 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2025.12.10.691922
Open in JClub

Follow this area in the app

Journals this month

All journals →

Moving areas, week to 3 Oct 2026

All research areas →

Read

Moved this week

Latest in HIV Research and Treatment

Browse JClub