Osteoclasts disrupt meningeal lymphatic drainage in dural metastasis, with significant impairment linked to tumor progression in a mouse model.
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Lymphatic System and Diseases
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Ablating endothelial PERK enhances DLL4-NOTCH3 signaling, boosting lymphoid regeneration by 50% after irradiation in hematopoietic recovery.
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Aerobic exercise enhances tumor vascular function and chemotherapy efficacy in pancreatic cancer by activating S1PR1 signaling in endothelial cells.
A six-gene lymphangiogenesis-related signature accurately predicts survival and reveals immune and molecular subtypes in cervical cancer.
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