Research area · week to 3 Oct 2026

Bacterial Genetics and Biotechnology

Moving in EMBO Journal, mBio.

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Substrate-induced assembly and functional mechanism of the membrane protein insertase SecYEG-YidC.
EMBO Journal · 1 Aug 2026 · Journal Article
Substrate-induced assembly of SecYEG-YidC facilitates membrane protein insertion without gate entry, revealing a conserved, thermodynamically driven mechanism.
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https://jclub.com.au/a/42362696
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Regulation of iron ion homeostasis in Staphylococcus aureus and its impact on physiology and virulence.
mBio · 8 July 2026 · Review
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https://jclub.com.au/a/42262075
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A conserved archaeal protein with evolutionary links to bacterial ribosome hibernation and eukaryotic energy sensing.
EMBO Journal · 2 Oct 2026 · Journal Article
AHA, a conserved archaeal ribosome-associated protein, links bacterial hibernation factors and eukaryotic energy sensors, revealing an evolutionary connection across domains.
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https://jclub.com.au/a/42823509
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The type VI secretion system governs strain maintenance in a wild mammalian gut microbiome.
eLife · 2 Oct 2026 · Journal Article
The T6SS on an ICE enables Bacteroides to maintain strain stability in a wild mammalian gut microbiome, with 20% of related species harboring this system.
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https://jclub.com.au/a/42826055
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Dual cytosine modification through hydroxylation and arabinofuranosylation in phages.
Nature Chemical Biology · 1 Oct 2026 · Journal Article
Coliphage HY126 encodes a novel dual cytosine modification system involving hydroxylation and diarabinofuranosylation, creating a unique DNA modification with two arabinofuranose units.
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https://jclub.com.au/a/41922540
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Corrigendum to "Precise control of transcriptional stoichiometry in bacteria: From mechanisms to synthetic biology applications" [Biotechnology Advances 86 (2026) 108748].
Biotechnology advances · 1 Oct 2026 · Published Erratum
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A non-canonical redox family protein regulates bacterial interaction machineries.
Cell Reports · 1 Oct 2026 · Journal Article
YdzF, a non-canonical regulator, controls bacterial nanotube formation in Gram-positive bacteria through YmdB-dependent flagellar gene regulation.
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https://jclub.com.au/a/42826100
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How proteins fold.
Nature Reviews Molecular Cell Biology · 1 Oct 2026 · Journal Article
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https://jclub.com.au/a/42393190
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From fragmented workflows to integrated pipelines: Bridging enzymatic DNA synthesis, assembly, and MutS-based error correction.
Biotechnology advances · 1 Oct 2026 · Review
Integrating enzymatic DNA synthesis, assembly, and MutS-based error correction into a continuous pipeline enhances fidelity and scalability for gene construction.
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https://jclub.com.au/a/42225240
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The role of intracellular ROS in the development of antimicrobial resistance:A convergent mediator linking mutations and horizontal gene transfer.
Environmental pollution · 1 Oct 2026 · Review
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https://jclub.com.au/a/42392292
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De novo-engineered guide RNA-directed transposition with TnpB-family proteins.
Molecular Cell · 1 Oct 2026 · Journal Article
De novo RNA-guided transposition systems using TnpB-family proteins achieve high-efficiency DNA insertion with precise control in bacteria.
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https://jclub.com.au/a/42753721
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The CUP pilus SMF-1 utilizes a specific antiparallel bundling mechanism to initiate biofilm formation.
Cell Reports · 1 Oct 2026 · Journal Article
SMF-1 pilus forms antiparallel bundles that facilitate rapid biofilm initiation in Stenotrophomonas maltophilia, revealing a unique structural mechanism for bacterial colonization.
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https://jclub.com.au/a/42826101
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A dichotomous family of Cache domain proteins evolved through c-type heme acquisition
bioRxiv · 1 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.01.703092
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Identification of Molecular Pathways Underlying Mn(II) Oxidation in Pseudomonas resinovorans.
Environmental microbiology · 1 Oct 2026 · Journal Article
Molecular pathways involving c-di-GMP regulators and biofilm components drive Mn(II) oxidation in Pseudomonas resinovorans MOB-513, with key genes identified.
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https://jclub.com.au/a/42823619
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A protein language model links the E. coli pangenome functional landscape geometry to host proteostasis
bioRxiv · 30 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.01.15.699719
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Growth-Aware Optogenetic Control for Cross-Scale Disturbance Rejection in Bacterial Batch Cultures
bioRxiv · 30 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.04.716495
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Conserved Obg-type GTPases Sustain Protein Synthesis across Domains of Life
bioRxiv · 30 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.13.724932
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The bacterial swarming factor SwrD belongs to a diverse family of proteins that form hexameric rings
bioRxiv · 30 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.26.727983
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Emergence of mutants in bacterial populations: a simulation-based approach for parameter inference in extended Luria & Delbru&x0308;ck scenarios
bioRxiv · 30 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2025.12.19.695396
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Dynamic protrusions mediate crawling motility in Asgard archaea.
Nature · 30 Sept 2026 · Journal Article
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https://jclub.com.au/a/42816618
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Nitrite reductase NirB mediates an unconventional nitrogen assimilation strategy to enhance adaptations of extremophile
bioRxiv · 28 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.23.753953
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A functional screen for bacterial ubiquitin regulation identifies an unusual Pseudomonas aeruginosa E3 ligase.
EMBO Journal · 28 Sept 2026 · Journal Article
A novel Pseudomonas aeruginosa E3 ligase, PUL-1, was identified as a key regulator of virulence, revealing a unique mechanism of bacterial ubiquitin manipulation.
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https://jclub.com.au/a/42806160
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Antagonistic small proteins enable magnesium-dependent tuning of two-component signaling
bioRxiv · 28 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.06.723403
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Loss of restriction-modification methyltransferases drives persistence to fluoroquinolones in Pseudomonas aeruginosa
bioRxiv · 26 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.26.754597
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Matrix-controlled emergence of biofilm architecture shapes antimicrobial survival
bioRxiv · 26 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.25.752283
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Host genetics determines the fate of the Lactobacillaceae population in the small intestine
bioRxiv · 26 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.25.754556
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Entry exclusion enables selective conjugative DNA delivery in synthetic bacterial communities.
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.24.754286
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WITHDRAWN: Blocking IF3N delays bacterial translation initiation
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.03.14.643242
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Extreme envelope plasticity drives temperature-dependent morphogenesis in the LPS-free bacterium Sphingobium yanoikuyae
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.04.730141
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Vesicle-associated exudates from Alteromonas enhance growth and survival of Prochlorococcus in batch culture.
Applied and environmental microbiology · 23 Sept 2026 · Journal Article
Alteromonas macleodii EZ55 exudates, including vesicles, significantly enhance Prochlorococcus MIT9312 growth and survival, with effects observed across all growth phases.
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https://jclub.com.au/a/42549905
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A functionally selected Acinetobacter sp. phosphoethanolamine transferase gene from the goose fecal microbiome confers colistin resistance in E. coli.
Applied and environmental microbiology · 23 Sept 2026 · Journal Article
A phosphoethanolamine transferase gene from goose fecal microbiome confers high-level colistin resistance in E. coli, highlighting environmental reservoirs of resistance genes.
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https://jclub.com.au/a/42560056
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The iron paradox and particle size sensing: transcriptomic response of Enterococcus faecalis to non-nutritive minerals.
Applied and environmental microbiology · 23 Sept 2026 · Journal Article
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