Journal of bacteriology
American Society for Microbiology · Microbiology & Mycology · ISSN 0021-9193, 1098-5530
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- 39
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Acinetobacter baumannii's success as a multidrug-resistant pathogen relies on adaptability and resilience rather than extensive virulence factors, exemplified by its ability to survive under severe stresses.
Salmonella Typhi exhibits significantly impaired acid stress resistance compared to Salmonella Typhimurium, with growth suppressed at pH 4.5 due to gene loss.
Cytidine base editors induce high rates (44%) of C:G to G:C transversions in certain Streptomyces strains, surpassing typical transition mutation outcomes.
Chloramphenicol exposure triggers transient, spatially regulated expression of multiple antibiotic resistance genes in Bacillus subtilis, including novel resistance to glycopeptides phleomycin and bleomycin.
The impact of RpoS status on 2-aminoacrylate stress in Salmonella enterica serovar Typhimurium ridA mutants reveals RpoS modulates metabolic responses to stress.
Pseudomonas bacteria enzymatically oxidize manganese from Mn(II) to Mn(III/IV), forming extracellular Mn oxides with potential ecological roles.
Bdellovibrio bacteriovorus employs a unique intrabacterial predatory lifestyle, rapidly invading and consuming gram-negative bacteria, with its molecular mechanisms still being unraveled.
Loss of YqeK in Staphylococcus aureus causes a 1,000-fold increase in Ap 4 N levels and impairs stress resistance and virulence gene expression.
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Membrane vesicles are crucial biofilm matrix components in Staphylococcus aureus, significantly enhancing biofilm formation by carrying DNA and other matrix elements.
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Prevotella species are essential for lung immune balance, with their depletion linked to reduced survival and increased infection risk in critically ill patients.
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Mutational analysis reveals key base pair requirements for NrdR binding in prokaryotic genomes, enabling precise identification of regulatory sites.
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Integrative and conjugative elements enable frequent chromosomal DNA recombination within Novosphingobium aromaticivorans, affecting about 10% of its genome.
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MbcS, a refunctionalized acyl-CoA synthetase in Staphylococcus aureus, provides a significant fitness advantage during intra-species competition under nutrient-limited conditions.
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C. difficile assembles a unique divisome complex in three phases, with PBP1 replacing FtsW-FtsI in septal peptidoglycan synthesis, highlighting a distinct bacterial division mechanism.
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Polyunsaturated fatty acids effectively kill glycolytic Staphylococcus aureus strains, including persisters and small colony variants, by inducing lipid peroxidation.
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Relocation of BdlA to the cell pole activates DipA, triggering motility gene expression and enabling Pseudomonas aeruginosa biofilm dispersion.
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PilU functions as a second, environmentally modulated T4P retraction motor in Myxococcus xanthus, essential for forceful motility and adaptive responses.
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Multiple toxin-antitoxin systems in Helicobacter pylori enhance its adaptability, with at least 20 validated systems influencing persistence and pathogenicity.
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RodZ activates the elongasome in Escherichia coli by triggering signaling pathways through MreCD and MreB, essential for lateral peptidoglycan synthesis.
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TrbA binds and locks KorB, a DNA-sliding clamp, to repress transcription on multi-drug resistance plasmids, revealing a conserved clamp-locking mechanism involving multiple regulators.
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De novo monounsaturated fatty acid synthesis is essential for streptococcal growth, stress tolerance, and membrane homeostasis across multiple pathogenic species.
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High levels of antisense transcription are conserved across multiple strains of Orientia tsutsugamushi, indicating a regulated gene expression mechanism during infection.
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Blocked transcription-translation complexes in bacteria are rescued through transcript release and trans-translation, preventing detrimental accumulation of stalled ribosomes.
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Pulcherriminic acid from Bacillus subtilis effectively disrupts yeast biofilms by chelating iron, offering a natural antibiofilm strategy with broad applications.
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Pseudomonas aeruginosa's flagellar motor operates with near-unbiased rotation, modulating dwell times rather than bias, revealing a novel chemotaxis mechanism.
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Salmonella enterica can assemble functional flagella without FlgJ’s cell-wall hydrolyzing activity, though at reduced efficiency, demonstrating diverse flagellar assembly mechanisms.
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Diverse accessory factors of the type VI secretion system (T6SS) in Gram-negative bacteria number over six functional categories, enhancing its adaptability and virulence.
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