The abstract is read at the publisher; the summary is JClub's.
The last bacterial common ancestor encoded a functionally complete flagellum, with 50 ancestral protein groups reconstructed from 80,789 bacterial proteomes.
- Why it matters: Prior work inferred only 24 ancestral flagellar genes, leaving uncertainty whether LBCA had a simpler system or whether divergence hid additional ancestral components.
- What they did: The authors combined large-scale homology searches, conserved sequence signatures, gene-tree clustering, and gene-neighborhood evidence across 80,789 proteomes to infer ancestral presence.
- The result: They found 49 high-confidence ancestral flagellar protein groups plus one likely component, enabling a reconstructed repertoire that implies extensive later lineage-specific loss and remodeling.
The findingWhy it mattersWhat they didThe result
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