Sleep and Wakefulness Research
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Latest in Sleep and Wakefulness Research
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Reorganization of anterior cingulate cortex-CA1 communication after learning selectively suppresses superficial CA1 neurons, aiding memory consolidation.
- Open access
Disrupting activity in a specific subset of dopaminergic neurons during memory consolidation impairs long-term memory by causing sleep fragmentation in Drosophila melanogaster.
- Open access
Deletion of tyrosine hydroxylase in approximately 25% of substantia nigra dopamine neurons significantly reduces food-anticipatory locomotion in mice.
Long-range Sst-Chodl inhibitory neurons in the neocortex actively promote sleep and synchronized cortical activity, especially during low-arousal states, in mice.
- Open access
Silencing cortical layer 6b in mice reduces EEG power and slows brain oscillations during wake and REM sleep, highlighting its role in brain state regulation.
- Open access
Prefrontal cortical high-frequency oscillation chains during REM sleep orchestrate unique hippocampal-cortical reactivation patterns, differing from NREM sleep by significant temporal organization.
- Open access
Locus coeruleus activity inversely correlates with hippocampal ripples during offline states, with LC firing decreasing 1-2 seconds before ripple onset in rats.
- Open access
A retracted trial undermines the first randomized evidence on checkpoint inhibitor dosing timing, casting doubt on the influence of circadian biology on immunotherapy efficacy.
Dronabinol significantly reduces PTSD-related nightmares, showing greater improvement than placebo with a mean CAPS-IV B2 score decrease of -1.50 in a 10-week trial involving 171 adults.
Hippocampal theta sweeps encode goal locations independently of movement, predicting navigational success with 87% accuracy in rats.
- Open access
- 1 cites
Goal-directed hippocampal theta sweeps predict upcoming trajectories and coordinate with prefrontal activity during navigation in rats.
- Open access
- 7 cites
Infraslow heart rate variability during sleep, driven by locus coeruleus activity, predicts memory consolidation across species with a critical LC activity threshold.
- Open access
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Journals this month
- bioRxiv5569
- medRxiv1746
- Environ Res485
- PNAS463
- Sci Adv439
- JAMA255
- Cell Rep210
- BMJ205
- Nat Commun177
- Environ Pollution170
- Lancet149
- Science138
- NEJM119
- Applied & Environ Microbio116
- Curr Biol116
- J Exp Bot115
- mBio109
- Nature104
Moving areas, week to 3 Oct 2026
- Single-cell and spatial transcriptomics10
- Artificial Intelligence in Healthcare and Education8
- CAR-T cell therapy research7
- Neuroinflammation and Neurodegeneration Mechanisms6
- Lung Cancer Treatments and Mutations5
- Diabetes Treatment and Management4
- Pancreatic and Hepatic Oncology Research4
- Photosynthetic Processes and Mechanisms4
- Genomics and Chromatin Dynamics4
- Gut microbiota and health4