Malaria Research and Control
Moving in bioRxiv, medRxiv, Nature Microbiology, Cell, eLife, mBio, Molecular therapy. Nucleic acids, mSystems.
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Latest in Malaria Research and Control
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Cell traversal by Plasmodium sporozoites triggers innate immune responses essential for protective T cell activation, with 100% dependence on cell wounding signals.
- 1 cites
Active migration of Plasmodium sporozoites through host cells is essential for achieving sterilizing T cell-mediated immunity after vaccination, regardless of intrahepatic development.
- Open access
- 1 cites
WNV infection induces durable neutralizing antibodies with a half-life of up to 472 days, but cross-reactivity against divergent lineages varies significantly among individuals.
- Open access
AP2-HS regulates environmental induction of sexual conversion in Plasmodium falciparum, involving a feedback loop that controls gdv1 expression and gametocyte formation.
Acyl carrier protein is vital for apicoplast biogenesis in Plasmodium falciparum blood-stage parasites, independent of its role in fatty acid synthesis, with knockout being lethal.
- Open access
Non-genetic variability in red blood cell hemoglobin content significantly influences hemoglobin consumption by Plasmodium falciparum, with infected cells amplifying this host heterogeneity.
- Open access
Multiple local PfDHFR I164L haplotypes have expanded in Uganda, increasing pyrimethamine resistance from 19.4% to 32.4% between 2016 and 2022.
- Open access
The structure of the Plasmodium falciparum moving junction reveals a sailboat-shaped complex that actively remodels host red blood cell membranes during invasion.
A lipid nanoparticle mRNA vaccine targeting Plasmodium vivax E140 antigen achieves up to 78% reduction in parasite invasion in human reticulocytes.
- Open access
Genomic surveillance uncovers widespread co-occurrence of drug resistance variants in Plasmodium falciparum across Ethiopia, threatening malaria control efforts.
- Open access
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