Research area · week to 3 Oct 2026

Hippo pathway signaling and YAP/TAZ

Moving in bioRxiv, Blood, EMBO Journal, Gastroenterology, Cancer Research, Communications Biology, eLife, EMBO Reports.

Moved this week: 0

Rebuilt 3 October 2026 at 2:42 pm AEST

Moved this week

Everything that moved →

Nothing in this area has moved yet this week.

Latest in Hippo pathway signaling and YAP/TAZ

Newest first · last 60 days

Reply.
Gastroenterology · 1 Oct 2026 · Letter
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42362095
Open in JClub
ID2 orchestrates the final 'E-scape' from the -165-kb Zeb2 enhancer for cDC1 specification.
Nature Immunology · 1 Oct 2026 · Journal Article
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42711530
Open in JClub
Critical Appraisal of the Integrin αV-YAP-CTGF Axis in Congestive Hepatopathy.
Gastroenterology · 1 Oct 2026 · Letter
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42362094
Open in JClub
A TBK1/ULK1 signalling axis couples lysosomal stress to TFEB activation.
Nature · 30 Sept 2026 · Journal Article
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42816627
Open in JClub
Identification of Transcriptional Hippo Response Signature Connecting Inflammatory Bowel Disease and Colorectal Cancer Progression
medRxiv · 26 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.09.24.26363887
Open in JClub
PolyA/polyQ-mediated conformational rewiring regulates DNA engagement and drives aggregation in the neuronal transcription factor Ascl1
bioRxiv · 25 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.05.11.724289
Open in JClub
VGLL4 enhances PDK4 transcription and promotes metabolic dysfunction-associated fatty liver disease.
EMBO Reports · 22 Sept 2026 · Journal Article
VGLL4 promotes MAFLD progression by enhancing PDK4 transcription, with overexpression causing steatosis and knockout offering protection in mice.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42773190
Open in JClub
Dorsal forerunner cells couple epiboly movements to zebrafish notochord extension
bioRxiv · 21 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.10.24.684459
Open in JClub
YAP1 induces hepatocellular carcinoma via DNA demethylation rather than by canonical driver gene mutations.
Communications Biology · 17 Sept 2026 · Journal Article
YAP1 induces hepatocellular carcinoma through DNA demethylation, not canonical driver gene mutations, with widespread demethylation activating oncogenes in mouse models.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42754661
Open in JClub
SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling.
Cancer Research · 15 Sept 2026 · Journal Article
SEPTIN7 promotes hepatocellular carcinoma progression and therapy resistance by stabilizing FGFR4 and enhancing its recycling, with knockout suppressing tumor development.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42406998
Open in JClub
Identification and SAR optimization of FBXO22-mediated TEAD Targeted Glue degraders
bioRxiv · 10 Sept 2026 · Preprint
Read the brief in JClub
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.04.21.719895
Open in JClub
Centrosome migration and apical membrane formation during epithelial polarization in MDCK cysts.
eLife · 8 Sept 2026 · Journal Article
Centrosome migration and apical membrane formation are hierarchically related but can occur independently during epithelial polarization in MDCK cysts, with centrosome positioning influenced by Par3.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42708509
Open in JClub
aPKC exclusion from the apical cortex in enteroblasts maintains stem cell homeostasis in Drosophila.
Journal of Cell Biology · 7 Sept 2026 · Journal Article
Exclusion of aPKC from the apical cortex in enteroblasts prevents overproliferation of intestinal stem cells in Drosophila midgut, maintaining tissue homeostasis.
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42412414
Open in JClub
Exponential growth and neuronal yield in the vertebrate developing retina are mediated by Hedgehog signaling
bioRxiv · 5 Sept 2026 · Preprint
Hedgehog signaling drives exponential growth and neuronal production in the developing vertebrate retina by regulating neural progenitor cell cycles.
- Open access
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2024.04.09.588672
Open in JClub
Design and experimental characterization of specificity-switching mutational paths of WW domains
bioRxiv · 4 Sept 2026 · Preprint
Read the brief in JClub
- Open access
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2025.12.08.693000
Open in JClub
Niche-targeted therapy via YAP/TAZ activation enhances hematopoietic regeneration.
Blood · 3 Sept 2026 · Journal Article
Activation of YAP/TAZ in bone marrow niche cells accelerates hematopoietic regeneration after myeloablative stress, with a notable enhancement in recovery.
- Open access
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42329810
Open in JClub
Local autophagy impairment triggers brain-wide presynaptic remodeling and resilience.
EMBO Journal · 1 Sept 2026 · Journal Article
Impairing autophagy in the Drosophila mushroom body triggers brain-wide presynaptic remodeling and enhances resilience, including increased sleep and lifespan.
- Open access
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42420489
Open in JClub
Spatial Transcriptomics As Rasterized Image Tensors (STARIT) characterizes cell states with subcellular molecular heterogeneity
bioRxiv · 1 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2025.12.18.695193
Open in JClub
Damage recognition by intestinal stem cells via Draper promotes adult Drosophila midgut regeneration.
EMBO Journal · 1 Sept 2026 · Journal Article
Draper-Src-Shark signalling in Drosophila intestinal stem cells detects tissue damage and drives proliferation, essential for midgut regeneration.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42557441
Open in JClub
Tyrosine phosphorylation and the inhibitory C-terminal SAM domain moderately affect transient interactions in a EphA2 cytoplasmic fragment in solution: A combined experimental and molecular modeling study.
bioRxiv · 27 Aug 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.09.29.679228
Open in JClub
Extracellular matrix regulates lineage plasticity in prostate cancer through YAP/TEAD
bioRxiv · 23 Aug 2026 · Preprint
Disruption of extracellular matrix-integrin-YAP/TEAD signaling triggers neuroendocrine lineage transition in prostate cancer, with significant implications for therapy resistance.
- Open access
- 3 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2025.12.30.697072
Open in JClub
Wound-Induced Syncytia Outpace Mononucleate Neighbors during Drosophila Wound Repair
bioRxiv · 20 Aug 2026 · Preprint
Read the brief in JClub
- Open access
- 4 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2023.06.25.546442
Open in JClub
Polar growth factor PgfA regulates polar peptidoglycan synthesis as well as mycolate synthesis in Mycobacterium smegmatis.
Journal of bacteriology · 20 Aug 2026 · Journal Article
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42447029
Open in JClub
Phosphatidylinositol 5-phosphate 4-kinase (PIP4K) regulates sugar homeostasis in Drosophila
bioRxiv · 16 Aug 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2025.12.03.692006
Open in JClub
Procr+ endothelial progenitor cells govern hematopoiesis through fine-tuning mesenchymal stem cell niche signals.
Blood · 13 Aug 2026 · Journal Article
Procr+ endothelial progenitor cells regulate hematopoiesis by activating MSC niche signals through a conserved Procr/HSPA8/Foxc2/Dll4 pathway.
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42101967
Open in JClub
ROCK-mediated junctional remodelling preserves barrier function in a developing epithelium during hypoxia
bioRxiv · 6 Aug 2026 · Preprint
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.06.29.735176
Open in JClub
Computational Binding Affinities of Disheveled PDZ Protein-Ligand Complexes
bioRxiv · 6 Aug 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.09.21.672002
Open in JClub

Follow this area in the app

Journals this month

All journals →

Moving areas, week to 3 Oct 2026

All research areas →

Read

Moved this week

Latest in Hippo pathway signaling and YAP/TAZ

Browse JClub