Prenatal Screening and Diagnostics
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Latest in Prenatal Screening and Diagnostics
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Reactivating the silenced embryonic ζ-globin gene restores therapeutic hemoglobin levels in severe α-thalassemia models, including lethal forms like Hb Bart's hydrops fetalis.
- Open access
De novo mitotic errors, including multipolar spindles and lagging chromosomes, occur frequently in late-stage preimplantation human embryos, with most lagging chromosomes passively inherited.
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- 12 cites
cfDNA-based non-invasive prenatal testing achieves 100% sensitivity and specificity for Trisomy 21, demonstrating high accuracy in detecting common fetal aneuploidies.
- Open access
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