Escherichia coli research studies
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Latest in Escherichia coli research studies
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The T6SS on an ICE enables Bacteroides to maintain strain stability in a wild mammalian gut microbiome, with 20% of related species harboring this system.
- Open access
- 1 cites
Intestinal epithelial cells presenting cytosol-delivered bacterial antigens program robust barrier immune memory, with significantly enhanced responses compared to bacterial retention.
- Open access
- 1 cites
Host N-glycosylation is essential for E. coli infection, facilitating adhesion and secretion system activity through two distinct pathways.
- Open access
Engineered native Escherichia coli strain MEc30 achieves lifelong gut colonization and sustained therapeutic delivery without disrupting host health or microbiota.
Dietary pectin triggers a microbiota-dependent high-IgA response in mice by remodeling bacterial surfaces with glycosphingolipids, notably HexCer (34:0).
Salmonella enterica can assemble functional flagella without FlgJ’s cell-wall hydrolyzing activity, though at reduced efficiency, demonstrating diverse flagellar assembly mechanisms.
- Open access
Multiple toxin-antitoxin systems in Helicobacter pylori enhance its adaptability, with at least 20 validated systems influencing persistence and pathogenicity.
- Open access
RodZ activates the elongasome in Escherichia coli by triggering signaling pathways through MreCD and MreB, essential for lateral peptidoglycan synthesis.
- Open access
In vivo CRISPRi screens reveal that E. coli adapts through distinct genetic strategies, with 20 essential genes varying across strains and conditions in the mouse gut.
MAIT cells exhibit tissue-dependent responses to S. aureus and show variable sensitivity to HlgAB toxin, with tonsillar MAIT cells being notably resistant.
- Open access
Burkholderia thailandensis switches from anti-bacterial T6SS-1 to anti-eukaryotic T6SS-5 during host cell invasion, with T6SS-1 activity causing host cell damage.
- Open access
Diverse bacterial glycoside transporters exhibit significant structural, functional, and taxonomic variation, with over 100 validated examples across multiple transporter families.
- Open access
ETBF toxin significantly promotes gall bladder cancer development in mice, with a BFT-dependent increase in tumor growth and proliferation.
- Open access
Gut microbiota influences EHEC infection severity, with beneficial microbes providing resistance and certain species promoting virulence, impacting disease outcomes.
- Open access
Manganese uptake via Sit and MntH is essential for UPEC CFT073 to resist oxidative stress and establish infection during urinary tract infections.
- Open access
Co-localized Zorya II, Druantia III, and ARMADA II systems on O-island 172 provide synergistic phage resistance in Escherichia coli strain EDL933, with Druantia III and ARMADA II being most effective.
- Open access
- 2 cites
Genomic analysis of 411 neonatal ExPEC strains reveals widespread virulence and resistance genes, with ST1193 and O75 being the most prevalent types across China.
- Open access
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