Research area · week to 3 Oct 2026

Gene expression and cancer classification

Moving in bioRxiv, Biotechnology advances, Journal of hepatology, medRxiv, Nature, Nature Communications.

Moved this week: 0

Rebuilt 3 October 2026 at 5:00 pm AEST

Moved this week

Everything that moved →

Nothing in this area has moved yet this week.

Latest in Gene expression and cancer classification

Newest first · last 60 days

Benchmarking niche identification via domain segmentation for spatial transcriptomics data
bioRxiv · 2 Oct 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.02.27.708202
Open in JClub
Defining transcriptomic niches in human fibrotic lung with multi-sample spatial transcriptomics analysis using the MAPLE algorithm
bioRxiv · 1 Oct 2026 · Preprint
Multi-sample spatial transcriptomics reveals distinct regional fibrotic programs and cellular niches in human IPF, with 10X Xenium validation confirming key findings.
- Open access
- 20 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2022.02.28.482296
Open in JClub
Programming the translational landscape for predictable gene expression.
Biotechnology advances · 1 Oct 2026 · Review
Engineering translation control enables predictable gene expression by tuning initiation, elongation, and termination processes in biological systems.
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42289258
Open in JClub
BatchVaria: variance-based evaluation of batch correction with provenance tracking
bioRxiv · 30 Sept 2026 · Preprint
BatchVaria reveals that subtype-protected ComBat maintains nearly unchanged subtype contributions after correction, unlike naive ComBat which reduces them by 4.23%.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.05.07.721996
Open in JClub
A gene program association study (GPAS) delineates novel patterns of lineage plasticity and aggressiveness in non-small cell lung cancer
bioRxiv · 27 Sept 2026 · Preprint
Read the brief in JClub
- Open access
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.05.06.652317
Open in JClub
fastACCORD enables ultrahigh-dimensional partial correlation modeling for multi-omic data integration
bioRxiv · 25 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.09.20.753046
Open in JClub
HR-FRGS: A Novel Biomarker Discovery Protocol using Dual Layer Hypergraph Learning for NGS RNA Sequence Data
bioRxiv · 25 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.09.21.753079
Open in JClub
ClustSIGNAL identifies cell types and subtypes using an adaptive smoothing approach for scalable spatial omics clustering
bioRxiv · 25 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2025.11.30.691081
Open in JClub
Transcriptomic Profiling and Demographic Analysis of Appalachian Patients with Pancreatic Ductal Adenocarcinoma using the Purity Independent Subtyping of Tumors (PurIST) Classifier
medRxiv · 23 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.09.22.26363302
Open in JClub
Efficient differential expression analysis of large-scale single-cell transcriptomics data using Dreamlet.
Nature Communications · 23 Sept 2026 · Journal Article
Dreamlet enables fast, memory-efficient differential expression analysis of large-scale single-cell transcriptomics data, accurately identifying gene-trait associations across 150 Alzheimer's cases.
- Open access
- 6 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42778542
Open in JClub
MIMoSA: A Tool for Model-Independent Comparison of Transcription Factor Binding Motifs
bioRxiv · 20 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.05.13.725009
Open in JClub
Locat: Joint enrichment and depletion testing identifies localized marker genes in single-cell transcriptomics
bioRxiv · 17 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.04.03.716370
Open in JClub
Constructing Gene Regulatory Network using Chatterjee's Rank Correlation with Single-cell Transcriptomic Data
bioRxiv · 17 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.09.17.676530
Open in JClub
Geometric influences on the regional organization of the mammalian brain
bioRxiv · 14 Sept 2026 · Preprint
A hierarchical, geometry-based method reveals more homogeneous brain regions across multiple mammalian species, emphasizing geometry's role in brain organization.
- Open access
- 8 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.01.30.635820
Open in JClub
Recovery of genomic and transcriptomic profiles from decades-old FFPE brain tissues
bioRxiv · 14 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.04.20.719637
Open in JClub
FlashDeconv reveals resolution horizons in atlas-scale spatial transcriptomics
bioRxiv · 11 Sept 2026 · Preprint
Read the brief in JClub
- Open access
- 2 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2025.12.22.696108
Open in JClub
Evaluating Few-Shot Meta-Learning using STUNT for Microbiome-Based Disease Classification
bioRxiv · 9 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.03.01.708821
Open in JClub
Confounded Time Intervals and Artificial Variance Suppression in MASLD Biomarker Reproducibility.
Journal of hepatology · 5 Sept 2026 · Letter
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42700821
Open in JClub
platpy: A spatial-first framework for multi-layer spatial transcriptomic analysis
bioRxiv · 5 Sept 2026 · Preprint
platpy enables precise multi-layer spatial transcriptomic analysis by treating physical coordinates as the core organizing principle, improving registration and analysis efficiency.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.05.26.727917
Open in JClub
Integrative multi-omics QTL colocalization maps regulatory architecture in aging human brain
medRxiv · 4 Sept 2026 · Preprint
Read the brief in JClub
- Open access
- 8 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.04.17.25326042
Open in JClub
Genome-Wide Uncertainty-Moderated Extraction of Signal Annotations from Multi-Sample Functional Genomics Data
bioRxiv · 3 Sept 2026 · Preprint
Consenrich improves genome-wide signal extraction from noisy multi-sample functional genomics data, achieving significant accuracy gains in challenging estimation tasks.
- Open access
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.02.05.636702
Open in JClub
OT-knn: a neighborhood-aware optimal transport framework for aligning spatial transcriptomics data
bioRxiv · 2 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.02.19.706743
Open in JClub
Toward predictable and programmable genetic circuits in plants.
Biotechnology advances · 1 Sept 2026 · Review
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42140530
Open in JClub
Redefining healthy human liver zonation using high-resolution spatial multiomics.
Journal of hepatology · 1 Sept 2026 · Journal Article
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42481275
Open in JClub
An Integrated Transcriptomic Landscape of Lung Cancer Identifies Tumor Clusters of Biological Significance
bioRxiv · 1 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.03.16.712177
Open in JClub
An expanded codebook of human transcription factor DNA-binding specificity.
Nature · 1 Sept 2026 · Journal Article
The expanded human transcription factor codebook reveals 130 new DNA-binding motifs for 177 TFs, enhancing understanding of gene regulation in the human genome.
- Open access
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42557334
Open in JClub
HESTIA: Scalable Multimodal Integration of Histology and High-Resolution Spatial Transcriptomics for Robust Spatial Domain Identification
bioRxiv · 31 Aug 2026 · Preprint
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.05.14.723098
Open in JClub
Coordinated dysregulation of modular gene activity in human neuropathologies
bioRxiv · 31 Aug 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.08.25.747130
Open in JClub
Trends in Machine Learning and Feature Selection Stability for Human Gut Microbiome (Shotgun Metagenomics) and Metabolomics Matched Datasets
bioRxiv · 29 Aug 2026 · Preprint
Machine learning models, especially Random Forest and XGBoost, achieve up to 20% higher feature selection stability in human gut microbiome multi-omics data.
- Open access
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.06.21.660858
Open in JClub
Gene expression inference from cell-free DNA using uncertainty-aware deep learning
bioRxiv · 28 Aug 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.02.10.705188
Open in JClub

Follow this area in the app

Journals this month

All journals →

Moving areas, week to 3 Oct 2026

All research areas →

Read

Moved this week

Latest in Gene expression and cancer classification

Browse JClub