BRCA gene mutations in cancer
Moving in medRxiv, Frontiers in Genetics, The Lancet Oncology, bioRxiv, Cancer Research, EMBO Journal, EMBO Reports, Nucleic Acids Research.
- Moved this week
- 0
Rebuilt
Moved this week
Nothing in this area has moved yet this week.
Latest in BRCA gene mutations in cancer
Newest first · last 60 days
Expanding cancer susceptibility testing to the general population requires careful evaluation of clinical and public health benefits, with evidence supporting its use mainly for well-established genes.
- 1 cites
Access to cancer genomics and precision oncology remains profoundly unequal worldwide, limiting benefits for millions of patients and hindering research progress.
- 10 cites
Disruption of the BRCA1 coiled-coil domain does not impair suppression of tandem duplications in mouse cells and tumor models, indicating a non-essential role in this process.
- Open access
European Health Data Space and biobanking integration could create a trustworthy, federated health research infrastructure in Europe, but faces significant governance and technical challenges.
- Open access
Sixty-two percent of transgender adults are willing to participate in genomics research, but concerns about harm and mistrust remain significant barriers.
- Open access
Effective communication behaviors in clinical encounters can enhance trust and improve participation of underrepresented populations in biobanking, as shown by preliminary findings.
- Open access
BRCA1 exon 11 interacts with TOPBP1 to specifically promote DNA end-resection during homologous recombination, crucial for tumor suppression.
- Open access
Preclinical models of pediatric brain tumors lack ancestral diversity, potentially skewing treatment responses and perpetuating health disparities in minority populations.
CHK2-dependent phosphorylation of MUS81 promotes DSB formation during replication stress, crucial for fork recovery in BRCA2-deficient human cells.
- Open access
Polygenic risk scores and family history together improve coronary heart disease prediction across diverse US populations, increasing true-positive detection by nearly 19%.
Follow this area in the app
Browse JClub
Journals this month
- bioRxiv5569
- medRxiv1746
- Environ Res485
- PNAS463
- Sci Adv439
- JAMA255
- Cell Rep210
- BMJ205
- Nat Commun177
- Environ Pollution170
- Lancet149
- Science138
- NEJM119
- Applied & Environ Microbio116
- Curr Biol116
- J Exp Bot115
- mBio109
- Nature104
Moving areas, week to 3 Oct 2026
- Single-cell and spatial transcriptomics10
- Artificial Intelligence in Healthcare and Education8
- CAR-T cell therapy research7
- Neuroinflammation and Neurodegeneration Mechanisms6
- Lung Cancer Treatments and Mutations5
- Diabetes Treatment and Management4
- Pancreatic and Hepatic Oncology Research4
- Photosynthetic Processes and Mechanisms4
- Genomics and Chromatin Dynamics4
- Gut microbiota and health4