Research area · week to 3 Oct 2026

Enzyme Catalysis and Immobilization

Moving in Biotechnology advances, bioRxiv, Nature Chemical Biology, Applied and environmental microbiology, Environmental research, Nature Computational Science, Nature Reviews Molecular Cell Biology, Plant Physiology and Biochemistry.

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Corrigendum to 'Expanding biotechnological applications of Yarrowia lipolytica: Key advances in the past decade' [Biotechnol. Adv. 88 (2026) 108835].
Biotechnology advances · 1 Oct 2026 · Published Erratum
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Shepherding enzymes.
Nature Chemical Biology · 1 Oct 2026 · Journal Article
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Artificial metalloenzymes in complex biological environments.
Nature Chemical Biology · 1 Oct 2026 · Review
Artificial metalloenzymes can be engineered to function effectively in complex biological environments, including cell lysates, surfaces, and intracellular spaces, overcoming previous limitations.
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Biocatalysis and biodegradation for efficient utilization of liquid n-alkanes.
Biotechnology advances · 1 Oct 2026 · Review
Microorganisms efficiently metabolize liquid n-alkanes, enabling complete mineralization and biocatalytic conversion for environmental and industrial applications.
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Flavin-dependent enzymes as multifunctional biocatalysts: A mechanistic perspective.
Biotechnology advances · 1 Oct 2026 · Review
Flavin-dependent enzymes demonstrate extensive catalytic promiscuity, enabling over 20 distinct non-native reactions through natural and engineered mechanisms.
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Improvement opportunities for P450 biocatalytic applications in the pharmaceutical industry.
Biotechnology advances · 1 Oct 2026 · Review
Enhancing P450 enzyme components with greater degrees of freedom can significantly expand biocatalytic applications in pharmaceutical manufacturing.
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Enzymes for CO(2) fixation: Discovery, engineering, and applications.
Biotechnology advances · 1 Oct 2026 · Review
Enzymatic CO2 fixation pathways can be optimized to convert CO2 into valuable products, with potential for scalable, sustainable biocatalytic applications.
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Two-phase anaerobic digestion with sub-thermophilic hydrolysis: Regulating metabolites to accelerate electron transfer and enhance methanogenesis.
Environmental research · 1 Oct 2026 · Journal Article
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Advances in amidases and urethanases as depolymerization biocatalysts.
Nature Chemical Biology · 1 Oct 2026 · Review
Metagenomic enzymes targeting stable bonds in plastics show promise but currently lack sufficient activity for efficient nylon and polyurethane depolymerization.
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Computational design of a thermostable α-helical barrel protein with tunable active-site positioning
bioRxiv · 25 Sept 2026 · Preprint
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Biochemical and structural characterization of AmyY from Alkalimonas sp. NCh-2 reveals a class of metal-free α-amylases in glycoside hydrolase family 13.
Applied and environmental microbiology · 23 Sept 2026 · Journal Article
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Bioengineered algal lipids enriched in structured medium- and long-chain triacylglycerols, linoleate, and sn-2 palmitate for human milk fat substitutes
bioRxiv · 22 Sept 2026 · Preprint
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How natural enzymes use noncanonical redox cofactors.
Nature Chemical Biology · 22 Sept 2026 · Journal Article
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Intuitive enzyme design with LLM agents.
Nature Computational Science · 22 Sept 2026 · Journal Article
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ACAD10 encodes two orphan enzymes in the ether lipid biosynthetic and salvage pathways
bioRxiv · 15 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.09.10.675409
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Interplay of stability and dynamics in the optimization of a highly proficient de novo enzyme
bioRxiv · 10 Sept 2026 · Preprint
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A sequence motif enables widespread use of noncanonical redox cofactors in natural enzymes.
Nature Chemical Biology · 9 Sept 2026 · Journal Article
A conserved RH/QxxR motif enables widespread use of noncanonical redox cofactors in natural enzymes, with Bos taurus ALDH3a1 achieving unprecedented turnover with NMN+.
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Genome-wide analysis of MsGDSL gene family reveals MsGDSL69 as a key regulator of salt stress responses in alfalfa.
Plant Physiology and Biochemistry · 1 Sept 2026 · Journal Article
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Bioaugmentation enabled simultaneous biodegradation of sulfadiazine and nitrification.
Environmental research · 1 Sept 2026 · Journal Article
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Ancient enzymes, new biotechnology applications.
Nature Reviews Molecular Cell Biology · 1 Sept 2026 · Journal Article
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Conjugative serine recombinase engineering enables genome integration in transformation-resistant bacteria and bioproduction pathway prototyping
bioRxiv · 1 Sept 2026 · Preprint
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From evolution to rational design: AI-driven engineering of safe and highly efficient food enzymes.
Biotechnology advances · 1 Sept 2026 · Review
AI-driven enzyme design achieves highly efficient and safe food enzymes, with advancements enabling the creation of novel biocatalysts and improved stability.
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Microbial biosynthesis of stilbenoids: A comprehensive review.
Biotechnology advances · 1 Sept 2026 · Review
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Advances in in vivo continuous evolution technologies for strain development and enzyme engineering.
Biotechnology advances · 1 Sept 2026 · Review
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Recent advances and challenges in the biomanufacturing of L-homoserine as a versatile C4 platform chemical.
Biotechnology advances · 1 Sept 2026 · Review
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Improving acetate metabolism of Pseudomonas putida KT2440 by evolutionary and rational engineering
bioRxiv · 31 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.08.21.746131
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Unlocking the hidden value of food waste: Critical insights into circular biorefineries via enzyme cocktails driven hydrolysis.
Biotechnology advances · 29 Aug 2026 · Review
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Polyunsaturated fatty acid synthase: structure, mechanism and applications for sustainable polyunsaturated fatty acid production.
Biotechnology advances · 28 Aug 2026 · Review
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Engineering and design of artificial enzymes for non-natural biocatalysis in whole cells.
Biotechnology advances · 23 Aug 2026 · Review
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Minicells derived from Escherichia coli Nissle 1917 for efficient phenylalanine degradation.
Applied and environmental microbiology · 19 Aug 2026 · Journal Article
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