Research area · week to 3 Oct 2026

Influenza Virus Research Studies

Moving in Virulence, PLOS Computational Biology.

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Subtype-specific neutralizing antibodies promote antigenic shift during influenza virus co-infection.
Virulence · 27 July 2026 · Journal Article
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D347G in PA is critical for the pathogenicity of H9N2 avian influenza A virus in mice.
Virulence · 2 Aug 2026 · Journal Article
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https://jclub.com.au/a/42543038
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Alignment-free prediction of cross-reactivity in influenza A (H3N2) anticipates antigenic drift.
PLOS Computational Biology · 11 Aug 2026 · Journal Article
FluEmbed predicts influenza A (H3N2) antigenic drift with high accuracy, achieving a Spearman correlation of 0.67-0.80 from RNA sequences without alignments.
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https://jclub.com.au/a/42579720
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Latest in Influenza Virus Research Studies

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Mathematical modelling of in vitro replication dynamics for multiple highly pathogenic avian influenza clade 2.3.4.4 viruses in chicken and duck cells.
bioRxiv · 1 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.04.22.649950
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The Potential Public Health Benefit of mRNA-1010 for Influenza Among Older Adults >=65 Years in the United States
medRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.20.26363308
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Highly Pathogenic Avian Influenza Viruses H5N1 and H5N5 in Red Foxes (Vulpes vulpes) in Norway during 2022-2024
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.25.754393
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Genetic diversity and phylogeography of swine influenza A virus in 2013-2022 in Europe using a harmonized genotyping nomenclature
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.21.753142
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Influenza A deletion-containing viral genome production is altered by metabolites, metabolic signaling molecules, and cyanobacterial extracts.
Applied and environmental microbiology · 23 Sept 2026 · Journal Article
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https://jclub.com.au/a/42622406
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An endonuclease inhibitor unlocks the PA-X shutoff mechanism in influenza A virus.
Cell Reports · 22 Sept 2026 · Journal Article
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https://jclub.com.au/a/42684885
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The RdRp Thumb-1 Pocket is a Conserved Target for Broad-Spectrum Antiviral Development
bioRxiv · 18 Sept 2026 · Preprint
The RdRp Thumb-1 pocket is a conserved allosteric site across ssRNA viruses, enabling broad-spectrum antiviral development with MDL-001 showing activity against multiple viruses.
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https://jclub.com.au/a/10.1101/2024.03.29.587401
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Pathogenesis of H5N1 Clade 2.3.4.4b in dry Jersey cows following intramammary inoculation shows within-host compartmentalization
bioRxiv · 18 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.03.04.709389
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Modifiers of Influenza Vaccine Immunity from over Ten Years of Serological Data
medRxiv · 12 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.01.07.25342310
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Divergent antibody-mediated population immunity to H5, H7 and H9 subtype potential pandemic influenza viruses
medRxiv · 11 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.09.08.25335309
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A reusable model of pangenome selection informs optimal surveillance strategies over vaccine introductions.
Genome Medicine · 7 Sept 2026 · Journal Article
A model incorporating negative frequency-dependent selection accurately predicts pneumococcal vaccine replacement dynamics, guiding surveillance strategies across diverse regions.
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https://jclub.com.au/a/42706540
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Sex differences in vaccine-induced neuraminidase cross-recognition impact H5N1 dissemination to the lower respiratory tract in mice
bioRxiv · 4 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.26.728011
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Meteorological Drivers of Influenza A and B Positivity in a Subtropical Chinese City: A Six-Year Surveillance Study Integrating Distributed Lag Non-Linear Models and Deep Learning
medRxiv · 3 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.07.13.25331478
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Embryonated chicken eggs clear systemic H3N2 influenza without RIG-I: transcriptomic evidence for innate sufficiency and brain immune privilege
bioRxiv · 3 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.11.723864
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Beyond Viral Load: A Mechanistic Model of Virus-Immune Dynamics and Age-Dependent Influenza Severity
bioRxiv · 31 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.03.26.714633
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Trimester-dependent vertical transmission of H5N1 influenza virus through placental and mammary routes impairs offspring development.
Nature Communications · 21 Aug 2026 · Journal Article
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https://jclub.com.au/a/42754611
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Bacterial co-infection and antimicrobial use in hospital-attended patients with laboratory-confirmed influenza infection: a systematic review and meta-analysis.
medRxiv · 19 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.29.26352034
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antigen-prime: Simulating coupled genetic and antigenic evolution of influenza virus
bioRxiv · 18 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.01.23.701420
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A rationally designed neuraminidase immunogen elicits humoral responses to a conserved viral site
bioRxiv · 14 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.08.08.743685
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Data Assimilation Substitutes for Biological Complexity in Hybrid Influenza Forecasting Models
medRxiv · 13 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.19.26353597
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Emergence of an antigenically drifted and reassorted influenza B virus at the end of the 2024-25 influenza season.
mBio · 12 Aug 2026 · Journal Article
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https://jclub.com.au/a/42328860
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HHBayes: A Flexible Bayesian Framework for Simulating and Analyzing Household Transmission Dynamics
medRxiv · 11 Aug 2026 · Preprint
HHBayes, an open-source R package, enables flexible Bayesian simulation and analysis of household transmission with accurate parameter estimation for diverse pathogens.
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https://jclub.com.au/a/10.64898/2026.04.01.26349903
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