Fungal Infections and Studies
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Latest in Fungal Infections and Studies
Newest first · last 60 days
PinA and XYP1 peptides demonstrate strong, stable binding to Candida albicans membranes, effectively inhibiting fungal growth in vitro without harming human cells.
IL-1 family signalling is essential for mucosal defense against systemic Candida albicans, preventing dissemination and mortality in neutropenic conditions.
- Open access
Olorofim achieved clinical success in over 73% of patients with disseminated coccidioidomycosis, including those with severe CNS involvement, in a phase 2b trial.
Forty-five percent of Ecuadorian field biologists show prior exposure to Histoplasma capsulatum, revealing significant occupational risk in endemic environments.
Advances in molecular techniques and point-of-care tests promise faster, more accurate diagnosis of invasive fungal infections, potentially saving lives and reducing resistance.
- Open access
Global warming promotes thermotolerance in fungi and alters human immunity, increasing the risk of emerging fungal infections like Candida auris and Rhodosporidiobolus fluvialis.
- Open access
Cryptococcus neoformans relies on surface-associated Dpp4 enzyme for virulence, with deletion reducing pathogenicity and delaying host mortality in animal models.
- Open access
Ahr1 transcription factor is essential for activating the NLRP3/IL-1β pathway, recruiting neutrophils, and clearing Candida albicans from the brain, with 100% dependence observed in vivo.
- Open access
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