Gene Regulatory Network Analysis
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Latest in Gene Regulatory Network Analysis
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Modulating complex oscillators to achieve multiple properties is feasible with a new framework that ensures parameter uniqueness and efficiency, validated across diverse systems.
Integrating enzymatic DNA synthesis, assembly, and MutS-based error correction into a continuous pipeline enhances fidelity and scalability for gene construction.
- Open access
Sublethal rifampicin triggers a dynamic transcription factor network in Escherichia coli, with early responses involving 709 genes and long-term adaptation involving 272 genes.
- Open access
DELPHAI predicts heterogeneous cellular responses to perturbation with outperforming all baseline methods by leveraging learned cell fitness filtering and gene-space retrieval.
- Open access
Biomedical world models spanning molecular to clinical scales can predict system responses to interventions, enabling proactive decision-making in medicine.
- Open access
Careful probabilistic modeling reveals that Fisher information naturally defines local metrics, shaping biological data analysis and clarifying metric choices in computational biology.
- Open access
Transferable signaling response signatures enable high-resolution reconstruction of in vivo cell signaling histories across diverse cell types.
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