Angiogenesis and VEGF in Cancer
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Latest in Angiogenesis and VEGF in Cancer
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LPL-positive endothelial cells promote T-cell homing and liver metastasis regression by enhancing antigen presentation and immune targeting.
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Lactate-activated GPR132 signaling promotes kidney cancer growth by sustaining mitochondrial function and lactate uptake, with GPR132 blockade impairing tumor progression.
Aerobic exercise enhances tumor vascular function and chemotherapy efficacy in pancreatic cancer by activating S1PR1 signaling in endothelial cells.
Blood flow-induced haemodynamic stress regulates liver sinusoidal endothelial cell Wnt signalling, controlling metabolic zonation in the liver.
- Open access
Procr+ endothelial progenitor cells regulate hematopoiesis by activating MSC niche signals through a conserved Procr/HSPA8/Foxc2/Dll4 pathway.
Menin is essential for normal megakaryopoiesis and represents a therapeutic target in myeloproliferative neoplasms, with its inhibition causing severe thrombocytopenia.
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