Research area · week to 3 Oct 2026

Diabetes, Cardiovascular Risks, and Lipoproteins

Moving in medRxiv, Gut, JAMA, Journal of hepatology, Annals of Internal Medicine, The lancet. Gastroenterology & hepatology.

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Latest in Diabetes, Cardiovascular Risks, and Lipoproteins

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The glucagon and GLP-1 receptor dual agonist DD01 for metabolic dysfunction-associated steatotic liver disease and steatohepatitis (DD01-DN-02): 12-week results from a randomised, double-blind, multicentre, placebo-controlled, phase 2 trial.
The lancet. Gastroenterology & hepatology · 1 Oct 2026 · Randomized Controlled Trial
DD01 significantly reduces liver fat by at least 30% in 76% of adults with MASH or MASLD after 12 weeks, outperforming placebo in a phase 2 trial.
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Effects of Reimbursement Policy Change on Utilization of Injectable Semaglutide for Type 2 Diabetes and on Glycemic Control Among Discontinuers: A Danish Nationwide Cohort Study
medRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.23.26363640
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A Synopsis of the 2025 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline for Lipid Management for Cardiovascular Disease Risk Reduction.
Annals of Internal Medicine · 15 Sept 2026 · Journal Article
The 2025 VA/DoD lipid management guideline recommends more intensive therapy for high-risk patients, including combination treatments and new risk assessment tools.
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https://jclub.com.au/a/42735406
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Pharmacist Led Nutritional Counselling as a Community Intervention for Obesity, Undernutrition, and Anaemia: Evidence from a 1135 Participant Prospective Interventional Study in India
medRxiv · 9 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.25.26351725
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Parental obesity and risk of metabolic dysfunction associated steatotic liver disease in adult offspring: UK birth cohort study.
Gut · 7 Sept 2026 · Journal Article
Pre-pregnancy parental obesity significantly increases the risk of adult offspring MASLD, with a 3.73-fold higher odds when both parents are overweight or obese.
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From evidence to action: The WHO-Imperial-EASL Collaborating Centre on Steatotic Liver Disease.
Journal of hepatology · 22 Aug 2026 · Editorial
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https://jclub.com.au/a/42632566
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Prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) among Children and Adolescents (<18 years) in India: A Systematic Review and Meta-analysis
medRxiv · 19 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.08.12.26360221
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Challenges and limitations of HbA1c in studies of advanced liver disease.
Journal of hepatology · 19 Aug 2026 · Letter
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https://jclub.com.au/a/42617918
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Prevalence of LDL-C Above 2026 Dyslipidemia Guideline Goals Among US Adults.
JAMA · 18 Aug 2026 · Journal Article
Over 50% of US adults with atherosclerotic cardiovascular disease have LDL-C levels above 2026 guideline targets, highlighting significant gaps in lipid management.
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New Dyslipidemia Guidelines Lower the Lipid Treatment Goals and Raise the Bar for Clinical Practice.
JAMA · 18 Aug 2026 · Comment
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Individual and Community-Level Determinants of Hypertension among Overweight and Obese Adults in Ethiopia: A Multilevel Analysis of Demographic and Health Survey Data
medRxiv · 17 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.08.12.26360341
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Cryptogenic steatotic liver disease: a lean phenotype associated with increased liver-related mortality.
Gut · 14 Aug 2026 · Journal Article
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