Biosensors with enzymatic amplification strategies for the detection of foodborne pathogenic microorganisms.

Biosensor platforms for foodborne pathogens integrate biorecognition with signal transduction, and recent work highlights enzymatic amplification strategies to improve detection across multiple food matrices.

• Why it matters: Rapid, specific pathogen detection is needed because foodborne microorganisms threaten public health, yet real samples create interference and enzymatic components can be unstable.
• What they did: The review systematically covers biosensors for common foodborne pathogens in matrices such as poultry, vegetables, dairy, and aquatic products, emphasizing signal amplification from enzyme catalysis to mimic-enzyme approaches.
• The result: It concludes that remaining barriers—enzyme stability, matrix interference, and reproducibility/standardization—must be addressed, and it recommends translation via advanced enzymes, sample pre-concentration, smart devices, and AI-driven analysis.

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