Chemigenetic DNA nanotrap for the mapping of norepinephrine in subcellular organelles.

Related in JClub

• bioRxivJClub

  A physiological Na+ signal activates mitochondrial PINK1 to couple synaptic depression to caspase-3-dependent spine pruning

  bioRxiv · 28 Oct 2026 · Preprint

  AI summary · may contain errors

  Na+ influx through NMDA receptors during chemically induced LTD depolarizes dendritic mitochondria, stabilizing and activating PINK1 to drive asynchronous mitochondrial fission linked to caspase-3-dependent spine pruning.

  • Open access

  Open

  Share

  Copy linkPost on XPost on BlueskyShare on LinkedIn

  https://jclub.com.au/a/10.64898/2026.05.29.728915

  Open in JClub
• PNASJClub

  Mitochondrial subpopulations promote cellular responses to changes in metabolic demand and signal transduction.

  Proceedings of the National Academy of Sciences · 27 Oct 2026 · Journal Article

  AI summary · may contain errors

  In mammalian cells under increased ATP demand, mitochondrial nucleoid components and mtDNA segregate to the oxidative subpopulation, while reductive mitochondria form in parallel.

  • Open access

  Open

  Share

  Copy linkPost on XPost on BlueskyShare on LinkedIn

  https://jclub.com.au/a/42905544

  Open in JClub
• bioRxivJClub

  Ribosome-Associated GTPase Drg1 Links Cytosolic Translation to Mitochondrial Homeostasis

  bioRxiv · 27 Oct 2026 · Preprint

  AI summary · may contain errors

  Drg1, a ribosome-associated GTPase in HEK293T cells, is required for mitochondrial homeostasis, with loss linked to reduced membrane potential and ATP production.

  • Open access
  • 1 cites

  Open

  Share

  Copy linkPost on XPost on BlueskyShare on LinkedIn

  https://jclub.com.au/a/10.64898/2026.02.23.707305

  Open in JClub