Alternative proteins could help meet the projected 50% increase in global meat demand by 2050, but large-scale production remains a significant challenge.
Transgenic Plants and Applications
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Red and far-red light treatment increases heterologous GFP and taxadiene production in Nicotiana benthamiana by over 57% and 76.5%, respectively, compared to white light.
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MDL-001 is the first broad-spectrum oral antiviral demonstrating in vivo efficacy against multiple RNA viruses, including influenza, RSV, SARS-CoV-2, and hepatitis B/C, with nanomolar potency.
- Open access
- 4 cites
NtEPF3 and NtEPFL6 peptides enhance drought tolerance in tobacco by regulating stomatal function and kinase signaling pathways.
- Open access
Dietary pectin triggers a microbiota-dependent high-IgA response in mice by remodeling bacterial surfaces with glycosphingolipids, notably HexCer (34:0).
Salicylic acid stabilizes NPR1 and enhances its interaction with MED15A, activating plant immunity through a specific molecular mechanism.
- Open access
Synthetic biology advances have enabled plants to serve as programmable chassis for producing high-value natural products, with recent pathway engineering achieving significant productivity gains.
Microbial cell factories can produce phytohormones at industrial scale, with advances in synthetic biology and AI enabling efficient, sustainable agriculture solutions.
Engineered attB(V111) site achieves up to 51.9% integration efficiency in human cells and 35.6% in rice, greatly enhancing site-specific recombination in plants and human cells.
- Open access
Hierarchical constraint management combined with AI enables scalable biomanufacturing of astaxanthin, overcoming nonlinear responses and optimization plateaus in complex biological systems.
CD19 CAR T cell therapy demonstrated acceptable safety and significant clinical improvements in six patients with treatment-refractory seropositive rheumatoid arthritis, with a median 34% DAS28-CRP reduction.
Three interconnected metabolic pathways collectively supply one-carbon units, essential for growth and virulence in Listeria monocytogenes, with a key role for the 1C-THF pool.
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