Axon Guidance and Neuronal Signaling
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Retinal waves, apoptosis, and angiogenesis are tightly synchronized during postnatal mouse retinal development, with apoptotic cells triggering neural activity and vascular growth.
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SLAP suppresses EPHB2-SFK signaling, preventing excessive colonic epithelial proliferation and tumor development, highlighting its role as a tumor suppressor in the colon.
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Hedgehog signaling drives exponential growth and neuronal production in the developing vertebrate retina by regulating neural progenitor cell cycles.
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A soma-driven cytoskeletal oscillator directs neuronal polarity by establishing a single axon in developing neurons.
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Large-scale hippocampal CA3 connectomics reveals a gradient of mossy fiber inputs and specific feedforward inhibition targeting pyramidal cell subtypes.
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