Evolution and Genetic Dynamics
Moving in bioRxiv, medRxiv, mSystems, Cancer Research, eLife, EMBO Journal, Nature Communications, Nature Microbiology.
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Latest in Evolution and Genetic Dynamics
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Cancers exhibit a four-fold higher mutation burden than normal tissues across five organs, driven by individual baseline mutation rate differences.
Learning significantly enhances behavioral individuality in genetically identical Drosophila, with persistent effects observed across 90 genetic backgrounds.
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Misinterpretation of microbial ecological dynamics as rapid evolution occurs in metagenomic time series due to methodological limitations.
- Open access
Sublethal rifampicin triggers a dynamic transcription factor network in Escherichia coli, with early responses involving 709 genes and long-term adaptation involving 272 genes.
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Transient changes in H3K27me3 in C. elegans persist for multiple generations, affecting fertility and involving specific histone modifications.
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In vivo CRISPRi screens reveal that E. coli adapts through distinct genetic strategies, with 20 essential genes varying across strains and conditions in the mouse gut.
Non-native Erigeron canadensis populations evolve increased competitive ability independently in two of four genetic clusters, enhancing invasion success under diverse conditions.
- Open access
Multiallelic genotypic selection can be modeled and estimated from time-series data, revealing complex fitness interactions such as heterozygote advantage in populations.
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Resistance genes can produce different antimicrobial resistance phenotypes depending on environmental and physiological context, highlighting resistance as a state rather than a fixed trait.
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