Colorectal Cancer Screening and Detection
Moving in Gastroenterology, Gut, The lancet. Gastroenterology & hepatology, Nature Medicine, mSystems, Nature Reviews Cancer, New England Journal of Medicine, The Lancet.
- Moved this week
- 0
Rebuilt
Moved this week
Nothing in this area has moved yet this week.
Latest in Colorectal Cancer Screening and Detection
Newest first · last 60 days
Having 5 to 10 nonadvanced adenomas significantly increases the risk of advanced colorectal neoplasm, with a 10.1% 5-year incidence, highlighting the need for tailored surveillance.
A blood-based assay detects colorectal cancer and advanced adenomas with 95% accuracy, showing 91% sensitivity for cancers and 81% for advanced adenomas in a multicentre study.
- 1 cites
AI-assisted colonoscopy in Lynch syndrome surveillance did not significantly increase adenoma detection rates, with a 33.8% rate compared to 30.9% in standard procedures.
- Open access
- 1 cites
Early-onset colorectal cancer (EOCRC) cases under age 50 are rising globally, with lifestyle and early-life factors contributing to the increasing burden.
The PATHFINDER 2 study found that a blood-based multi-cancer early detection test achieved a cancer detection rate of 0.54% with high specificity and positive predictive value in adults aged 50 and older.
- Open access
- 2 cites
Multicancer early-detection blood tests did not significantly reduce stage III or IV cancer incidence after three screening rounds in a large trial of over 142,000 participants.
- 2 cites
The multi-cancer early detection test demonstrated a positive predictive value of up to 58% and detected primary cancers in 0.60% to 0.41% of participants across three screening rounds in NHS screening.
- Open access
- 1 cites
Patient navigation and mailed FIT outreach significantly increase colorectal cancer screening uptake, especially in populations with low baseline rates, with risk ratios of 1.58 and 1.36 respectively.
- 2 cites
Exposure-driven processes may cause accelerated colorectal carcinogenesis, accounting for up to 20% of early-onset and post-colonoscopy CRC cases, challenging current prevention models.
- Open access
Follow this area in the app
Browse JClub
Journals this month
- bioRxiv5569
- medRxiv1746
- Environ Res483
- PNAS463
- Sci Adv439
- JAMA255
- Cell Rep210
- BMJ199
- Nat Commun177
- Environ Pollution170
- Lancet149
- Science138
- NEJM119
- Applied & Environ Microbio116
- J Exp Bot115
- Curr Biol112
- mBio109
- Nature104
Moving areas, week to 3 Oct 2026
- Single-cell and spatial transcriptomics10
- Artificial Intelligence in Healthcare and Education8
- CAR-T cell therapy research7
- Neuroinflammation and Neurodegeneration Mechanisms6
- Lung Cancer Treatments and Mutations5
- Diabetes Treatment and Management4
- Pancreatic and Hepatic Oncology Research4
- Photosynthetic Processes and Mechanisms4
- Genomics and Chromatin Dynamics4
- Gut microbiota and health4