Adipokines, Inflammation, and Metabolic Diseases
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Latest in Adipokines, Inflammation, and Metabolic Diseases
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ENPP1 prevents extracellular cGAMP accumulation in brown adipose tissue, reducing insulin resistance and obesity in high-fat diet conditions.
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Brown adipose tissue reduces hepatic oxidative stress by releasing 3-hydroxystearic acid, a cold-induced metabolite that modulates liver mitochondrial function.
Genetic analysis reveals shared downstream pathways involving cytoskeletal reorganization in depression and obesity, despite limited evidence for bidirectional causality.
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