Editor's Note: Blocked Autophagy Using Lysosomotropic Agents Sensitizes Resistant Prostate Tumor Cells to the Novel Akt Inhibitor AZD5363.

Clinical Cancer Research · 2 Nov 2026 · Published Erratum · Open access

Lamoureux, Thomas + more

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A USP28-TM9SF3-Golgiphagy axis maintains glycosylation homeostasis and promotes breast cancer progression.
EMBO Journal · 19 Oct 2026 · Journal Article
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USP28 sustains TM9SF3-dependent Golgiphagy by removing K48-linked ubiquitin chains, maintaining Golgi glycosylation fidelity and supporting breast cancer cell proliferation.
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LC3 forms functional nanoclusters on autophagosomes.
EMBO Reports · 1 Nov 2026 · Journal Article
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LC3B forms approximately 150 nm nanoclusters on autophagosomes that are essential for autophagy functions, including bacterial entrapment and motility.
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Editor's Note: Blocked Autophagy Using Lysosomotropic Agents Sensitizes Resistant Prostate Tumor Cells to the Novel Akt Inhibitor AZD5363.

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A USP28-TM9SF3-Golgiphagy axis maintains glycosylation homeostasis and promotes breast cancer progression.

LC3 forms functional nanoclusters on autophagosomes.

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