A metabolic boost to mRNA vaccines.

Nature materials · 1 Nov 2026 · Journal Article

Chada, Wilson

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Crosslinked ionizable lipids reprogram dendritic cell metabolism for potent mRNA vaccination.
Nature materials · 1 Nov 2026 · Journal Article
AI summary · may contain errors
Crosslinked ionizable lipid C12-2aN LNPs reprogram dendritic cell metabolism to enhance mRNA vaccination, yielding stronger SARS-CoV-2 pseudovirus neutralization and improved OVA cancer survival versus control LNPs.
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A metabolic boost to mRNA vaccines.

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