Nuclear speckles of GC richness.

Nature Reviews Molecular Cell Biology · 1 May 2026 · Journal Article

Zlotorynski

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Limits of deep-learning-based RNA prediction methods.
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AlphaFold3 and Boltz-1 deliver the best RNA structure predictions on an independent non-redundant dataset, but accuracy drops sharply for structurally divergent monomeric RNAs.
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Blocked transcription-translation complexes are rescued by transcript release followed by trans-translation.
Journal of Bacteriology · 17 Sept 2026 · Journal Article
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Translating ribosomes trapped in blocked transcription-translation complexes are rescued in bacteria when they trigger nascent transcript release from RNA polymerase, followed by trans-translation.
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In extracto cryo-EM reveals eEF2 as a major hibernation factor on 60S and 80S particles.
eLife · 3 Sept 2026 · Journal Article
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eEF2 is the most abundant hibernation factor, bound to >95% of 80S ribosomes and also to 60S subunits in mammalian lysates.
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- 6 cites
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Nuclear speckles of GC richness.

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Limits of deep-learning-based RNA prediction methods.

Blocked transcription-translation complexes are rescued by transcript release followed by trans-translation.

In extracto cryo-EM reveals eEF2 as a major hibernation factor on 60S and 80S particles.

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