Blood disorders and treatments
Moving in Blood, Gut, Nature Reviews Cancer, The lancet. Gastroenterology & hepatology, bioRxiv, Nature Genetics.
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Latest in Blood disorders and treatments
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Neutrophils predominantly promote tumor growth and metastasis in cancer, but can also mediate tumor cell killing depending on environmental cues.
Genomic and epigenomic profiling reveal over 40 molecular subtypes of acute lymphoblastic leukemia, enhancing classification and informing treatment strategies.
Mutant IDH1 causes a reversible block in neutrophil differentiation by repressing myeloid transcription programs in hematopoiesis.
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Loss of Stag2 causes GATA1 to reprogram its binding from erythroid to megakaryocyte targets, disrupting normal blood cell development in MDS models.
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