Microbial systems have been engineered to significantly enhance the biosynthesis of SAM and its derivatives, enabling sustainable production of high-value compounds.
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Moving in Journal of Experimental Botany, Plant, Cell & Environment, bioRxiv, Nature Chemical Biology, Biotechnology advances, Nature Microbiology, Plant Physiology and Biochemistry.
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Microbial systems have been engineered to significantly enhance the biosynthesis of SAM and its derivatives, enabling sustainable production of high-value compounds.
Elevated trigonelline levels and BrNANMT gene activity increase clubroot susceptibility in Brassica rapa, with overexpression worsening disease and gene loss enhancing resistance.
Nitrogen status influences grapevine metabolic response to sulfur deficiency, with sulfur deficiency causing a massive accumulation of nitrogen-rich amino acids and increased transpiration.
Reciprocal regulatory networks coordinate sulfur with phosphorus, nitrogen, and iron in plants, with key transcription factors controlling nutrient homeostasis in Arabidopsis thaliana.
The LSU protein family plays a crucial role in plant growth and stress resilience, extending beyond sulfur deficiency responses, with recent evidence highlighting their broader functions.
Sulfur assimilation regulates micronutrient homeostasis and detoxification in plants, with S pathways influencing over 20 essential trace element processes.
Cysteine synthase complexes in plants are dynamic regulators that integrate metabolic status with stress responses across multiple cellular compartments.
Microbial co-culture engineering enables first successful biosynthesis of 2-phenylethyl glucosinolate from phenylalanine, achieving significant titer improvements.
Sulfur metabolism intricately regulates autophagy in plants, with metal stress triggering a surge in sulfur-related responses and autophagic activity.
Low-sulfur conditions induce a conserved set of genes in rice roots, with SULTR1;1 promoting root growth under sulfur limitation in both upland and lowland varieties.
Cysteine desulfhydrases in photosynthetic organisms produce hydrogen sulfide, crucial for plant stress responses and physiological regulation, highlighting cysteine's central role.
Elevating methionine levels in plants alters development, stress responses, and epigenetic regulation, but is constrained by the plant’s metabolic control mechanisms.
Sulfur deficiency combined with water deficit triggers a synergistic redox response in pea leaves, involving 38 genes and increased glutathione S-transferase activity.
Sulfur metabolism is a key driver of plant-microbe interactions, influencing microbiome assembly, disease resistance, and nutrient cycling in sulfur-limited systems.
Hydrogen sulfide (H2S) enhances plant resilience to climate-induced abiotic stresses through protein persulfidation, with a significant role in stress regulation.
Sulfur metabolism regulates chloroplast retrograde signaling, with PAP levels linked to stress responses in plants, highlighting a key connection in Arabidopsis thaliana and beyond.
MTA overaccumulation in Arabidopsis reproductive tissues reduces sulfur metabolites and alters methylation, impairing development and fertility.
Manipulating the BnaA02.GLN1;2 gene increases glutamine synthetase activity, boosting nitrate uptake and seed yield in Brassica napus by up to nearly double under high nitrogen conditions.
MESH1 acts as a PAPS phosphatase, hydrolyzing PAPS into adenosine-5'-phosphosulfate and phosphate, thereby regulating sulfation in metazoans.
Salmonella's unique sulfate reductases with [4Fe-4S] clusters enhance gut colonization and systemic infection in mice, independent of molybdenum cofactors.
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