Research area · week to 3 Oct 2026

Photoreceptor and optogenetics research

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Latest in Photoreceptor and optogenetics research

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In conversation with Miguel Nicolelis.
Nature Neuroscience · 1 Oct 2026 · Interview
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https://jclub.com.au/a/42823470
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Streamlined Production of Recombinant Adeno-Associated Viruses Using Gateway Cloning Technology for Neural Circuit All-Optical Interrogation
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.22.752944
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How opsins diversified after the teleost whole-genome duplication: Insights from two parietopsins of the red piranha, Pygocentrus nattereri
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.09.17.675483
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Direct voltage imaging of peripheral axons in vivo reveals ongoing nociceptor firing in healthy mice
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.19.752889
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Brain state shapes the polarity of pulsed infrared neural stimulation responses in individual cortical neurons
bioRxiv · 25 Sept 2026 · Preprint
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An integrated platform for simultaneous wide-field voltage/calcium imaging and fMRI (EPI & ZTE) reveals neuronal infraslow dynamics underlying functional connectivity
bioRxiv · 22 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.01.26.701889
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On the feasibility of temporal interference stimulation of human brains using two arrays of electrodes
bioRxiv · 17 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.03.31.715653
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Molecular identification of wide-field amacrine cells in mouse retina that encode stimulus orientation
bioRxiv · 17 Sept 2026 · Preprint
Bhlhe22 and Kappa Opioid Receptor-expressing wide-field amacrine cells in mouse retina encode stimulus orientation with Ca2+ signals aligned to dendritic structure.
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https://jclub.com.au/a/10.1101/2023.12.28.573580
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Molecular mechanism of calcium inhibition in viral channelrhodopsins.
Nature Communications · 16 Sept 2026 · Journal Article
Calcium inhibits viral channelrhodopsins by binding near the retinal cofactor, blocking essential conformational changes and preventing ion translocation.
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https://jclub.com.au/a/42749743
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Anesthesia unconsciousness recruits dynamic parabrachial activity within a distributed brain-wide ensemble
bioRxiv · 15 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.03.28.646066
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Human-Specific Regulation of CHD2 Controls the Tempo of Cortical Development through Lysosomal Homeostasis
bioRxiv · 14 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.01.21.634145
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Local optogenetic control of genome editing and tumorigenesis in vivo using wireless implantable optoelectronics
bioRxiv · 10 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.06.12.659214
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Zapit: Open Source Laser-Scanning Photostimulation For Neuroscience
bioRxiv · 10 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.02.12.579892
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A cortical code emerges in Layer5a of S1 through temporal integration of thalamic inputs
bioRxiv · 10 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.06.11.658272
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ProteinSage: From implicit learning to explicit structural constraints for efficient protein language modeling
bioRxiv · 9 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.03.17.712034
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Quantum Sensing Reveals Chemotherapy Induced Persistent Oxidative Footprints in Fixed Brain Cancer Cells
bioRxiv · 7 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.07.27.666994
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Signaling mechanism of the transmembrane energy receptor Aer
bioRxiv · 6 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.25.727702
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Superior colliculus neurons encode and causally shape somatosensory decisions
bioRxiv · 4 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.01.735970
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Toward Pathology-guided Illumination Optimization for Neuromodulation with PhomiNeuro
bioRxiv · 4 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.04.736179
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Innervated human cardiac muscle model reveals sympathetic drivers of KCNH2-associated arrhythmias.
Nature Communications · 2 Sept 2026 · Journal Article
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https://jclub.com.au/a/42686760
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Multichannel optical cochlear implants enable spectrally distinct auditory activity
bioRxiv · 1 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.15.725096
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Molecular clockwork hypothesis for the KaiABC circadian oscillations
bioRxiv · 1 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.07.723666
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Targeted cortical stimulation reveals principles of cortical contextual interactions
bioRxiv · 31 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2022.06.22.497254
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Core promoters restrict pleiotropic enhancer inputs to achieve spatiotemporal specificity in gene expression
bioRxiv · 26 Aug 2026 · Preprint
Core promoters function as active gatekeepers, restricting enhancer inputs to generate precise spatiotemporal gene expression patterns in Drosophila.
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https://jclub.com.au/a/10.1101/2025.09.23.678065
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Increased layer 5 Martinotti cell excitation reduces pyramidal cell population plasticity and improves learned motor execution
bioRxiv · 21 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.03.10.584276
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A genome-wide in vivo CRISPR screen identifies neuroprotective strategies in the mouse and human retina.
Neuron · 19 Aug 2026 · Journal Article
Overexpression of UFD1 and UXT prevents photoreceptor degeneration in mouse and human P23H retinitis pigmentosa models, offering promising mutation-agnostic therapies.
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Intranasal photobiomodulation as an energy-efficient, largely parameter-insensitive alternative to transcranial photobiomodulation
bioRxiv · 18 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.08.08.743717
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A two-oscillator SCN model with period adaptation and systemic feedback captures photoperiod and T-cycle aftereffects in vivo and in explants
bioRxiv · 18 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.08.09.743784
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Impaired lysine biosynthesis drives constitutive energy stress priming and darkness stress responses
bioRxiv · 10 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.09.10.675385
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Evidence for the acquisition of a proteorhodopsin-like rhodopsin by a chrysophyte-infecting giant virus
bioRxiv · 10 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.06.17.660233
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