Cortical and brainstem circuits, especially the ventrolateral periaqueductal gray, causally mediate multimodal placebo analgesia in mice, with lasting effects after injury.
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- 7 cites
Pain Management and Placebo Effect
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A neuro-computational method reveals mental images are better represented by blurred, low-contrast, and psychedelic-style features, supporting theories of reduced sensory quality.
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Patient-centered opioid tapering achieves about 50% success without added benefit from behavioral support strategies in a U.S. trial of 562 adults.
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Cortical and brainstem circuits, especially the ventrolateral periaqueductal gray, causally mediate multimodal placebo analgesia in mice, with lasting effects after injury.
- Open access
- 7 cites
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