Lysosomal lipid and protein changes in the aging brain show increased myelin components and disrupted sphingolipid breakdown, especially in microglia, indicating dysfunction.
- Open access
Sphingolipid Metabolism and Signaling
Moving in bioRxiv, Cell Reports, Cancer Research, EMBO Reports, Nature Chemical Biology, Nature Communications.
- Moved this week
- 0
Rebuilt
Moved this week
Nothing in this area has moved yet this week.
Latest in Sphingolipid Metabolism and Signaling
Newest first · last 60 days
ExoU secreted by P. aeruginosa increases lysophosphatidylcholine levels, activating inflammasomes and causing cell death, with significant implications for cystic fibrosis infections.
- Open access
Aurora A kinase enhances inflammasome activation, increasing inflammation and bacterial survival in antibiotic-resistant Staphylococcus aureus infections.
- Open access
Aerobic exercise enhances tumor vascular function and chemotherapy efficacy in pancreatic cancer by activating S1PR1 signaling in endothelial cells.
MESH1 acts as a PAPS phosphatase, hydrolyzing PAPS into adenosine-5'-phosphosulfate and phosphate, thereby regulating sulfation in metazoans.
Follow this area in the app
Browse JClub
Journals this month
- bioRxiv5569
- medRxiv1746
- Environ Res485
- PNAS463
- Sci Adv439
- JAMA255
- Cell Rep210
- BMJ205
- Nat Commun177
- Environ Pollution170
- Lancet149
- Science138
- NEJM119
- Applied & Environ Microbio116
- Curr Biol116
- J Exp Bot115
- mBio109
- Nature104
Moving areas, week to 3 Oct 2026
- Single-cell and spatial transcriptomics10
- Artificial Intelligence in Healthcare and Education8
- CAR-T cell therapy research7
- Neuroinflammation and Neurodegeneration Mechanisms6
- Lung Cancer Treatments and Mutations5
- Diabetes Treatment and Management4
- Pancreatic and Hepatic Oncology Research4
- Photosynthetic Processes and Mechanisms4
- Genomics and Chromatin Dynamics4
- Gut microbiota and health4