Medical Imaging Techniques and Applications

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Soft tissue-to-bone ratio above 0.5 on routine whole-body bone scintigraphy in 8,769 Austrian patients without cardiac uptake is linked to higher all-cause mortality (aHR 1.73).

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In a histopathology-validated cohort of 61 IDH-wildtype glioblastoma patients (472 tissue samples), [18F]FET PET detects non-contrast-enhancing tumor tissue far better than CE-MRI (91.2% vs 52.6% sensitivity).

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Theranostics in oncology integrates diagnostic imaging and radionuclide therapy using matched probes, and clinical progress is linked to a promising future for multiscale approaches.

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A machine-learning framework using a computational brain-function model and FDG-PET predicts AD-type tau measured by flortaucipir-PET across AD and ADRD, with participant-level R² up to ~0.71.

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AI-assisted and structure-guided methods now enable identification of PET-degrading enzymes with industrial relevance, surpassing traditional bioprospecting approaches.